{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T12:19:29Z","timestamp":1777810769276,"version":"3.51.4"},"reference-count":25,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[1990,6,1]],"date-time":"1990-06-01T00:00:00Z","timestamp":644198400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[1990,6]]},"abstract":"<jats:p>The amounts of loosely-bound fluoride (F) deposited on human enamel by two topical F treatments were measured with use of a constant-composition F washing method. Enamel biopsies conducted before treatment and after the washing were used for determination of the firmly-bound F uptake. The results showed that (1) the washing system did not remove F from untreated enamel surface, (2) a four-minute application of an acidulated phosphate fluoride (APF) gel deposited 27.2 (2.4) (mean, S.E.) \u03bcg of loosely-bound Fper cm2 of enamel surface and 186 (111) ppm of firmly-bound F in the outer 10 \u03bcm of enamel, and (3) a four-minute application of a pH-2.1 dicalcium phosphate dihydrate (DCPD)-forming solution followed by APF produced 44.9 (3.1) \u03bcg\/cm2 of loosely-bound F and 1280 (354) ppm of firmly-bound F in the outer 10 \u03bcm of enamel. The results showed that the DCPD pre-treatment effectively enhanced the enamel reactivity with F, so that the DCPD-APF treated enamel acquired greater amounts of both loosely-bound F and firmly-bound F than did samples treated with APF alone.<\/jats:p>","DOI":"10.1177\/00220345900690060701","type":"journal-article","created":{"date-parts":[[2010,11,28]],"date-time":"2010-11-28T21:14:56Z","timestamp":1290978896000},"page":"1261-1265","source":"Crossref","is-referenced-by-count":26,"title":["Assessment of Loosely-bound and Firmly-bound Fluoride Uptake by Tooth Enamel from Topically Applied Fluoride Treatments"],"prefix":"10.1177","volume":"69","author":[{"given":"B.","family":"Sieck","sequence":"first","affiliation":[{"name":"American Dental Association Health Foundation, Paffenbarger Research Center, National Institute of Standards and Technology, Gaithersburg, Maryland 20899"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Takagi","sequence":"additional","affiliation":[{"name":"American Dental Association Health Foundation, Paffenbarger Research Center, National Institute of Standards and Technology, Gaithersburg, Maryland 20899"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.C.","family":"Chow","sequence":"additional","affiliation":[{"name":"American Dental Association Health Foundation, Paffenbarger Research Center, National Institute of Standards and Technology, Gaithersburg, Maryland 20899"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1990,6,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1159\/000260700"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1159\/000260873"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(75)90023-0"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1159\/000260836"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1177\/00220345750540013901"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1159\/000260540"},{"key":"atypb7","first-page":"299","volume":"68","author":"Chow, L.C.","year":"1989","journal-title":"J Dent Res"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1177\/00220345860650030201"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1159\/000260598"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1159\/000260591"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.1984.tb01450.x"},{"key":"atypb12","first-page":"263","volume":"65","author":"Hare, M.","year":"1986","journal-title":"J Dent Res"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(70)90009-9"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1177\/00220345880670100101"},{"key":"atypb15","unstructured":"Johansen, E. (1965): Comparison of Ultrastructural and Chemical Composition of Sound and Carious Enamel from Human Permanent Teeth. In: Tooth Enamel, M. V. Stack and R. W. Fearnhead, Eds. 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