{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T12:30:18Z","timestamp":1777811418954,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1992,3,1]],"date-time":"1992-03-01T00:00:00Z","timestamp":699408000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[1992,3]]},"abstract":"<jats:p>\n                    A previous study showed that a two-solution fluoride (F) rinse deposited significantly more loosely-bound F on the tooth surface than did a sodium fluoride (NaF) rinse with the same F concentration (12 mmol\/L). In the present study, this experimental rinse was evaluated for its ability to cause remineralization of enamel lesions in an in vitro pH-cycling model. Caries-like lesions were formed in the enamel of extracted human molars by means of a pH 4 demineralizing solution. Fifty-one ~120-\u03bcm-thick sections containing lesions were randomly divided into (1) control, (2) NaF rinse, and (3) two-solution F rinse groups. With the cut surfaces protected, the control samples were immersed in a pH 7 remineralizing solution for 12 days, and twice daily the sections were also exposed to a pH 4 demineralizing solution for 30 min. Samples in the NaF group received an additional one-minute rinse with a NaF (12 mmol\/L) solution twice daily. Samples in the two-solution rinse group received the rinse treatment with a 12 mmol\/L F solution prepared by combination of a Na\n                    <jats:sub>2<\/jats:sub>\n                    SiF\n                    <jats:sub>6<\/jats:sub>\n                    and phosphate-containing solution with a calcium solution just before use. The mineral contents of the lesions were assessed by quantitative microradiography. The results showed that (1) no significant de- or remineralization was detected in the controls; (2) a 46% decrease in mineral loss (AZ) ofthe lesion was produced by the NaF rinses; and (3) a 94% decrease in AZ and a 20-\u03bcm-thick, mineral-dense surface-coating were produced by the two-solution F rinse treatment.\n                  <\/jats:p>","DOI":"10.1177\/00220345920710030401","type":"journal-article","created":{"date-parts":[[2010,11,28]],"date-time":"2010-11-28T21:14:56Z","timestamp":1290978896000},"page":"443-447","source":"Crossref","is-referenced-by-count":29,"title":["Effect of a Two-solution Fluoride Mouthrinse on Remineralization of Enamel Lesions in vitro"],"prefix":"10.1177","volume":"71","author":[{"given":"L.C.","family":"Chow","sequence":"first","affiliation":[{"name":"American Dental Association Health Foundation, Paffenbarger Research Center, Polymers Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Takagi","sequence":"additional","affiliation":[{"name":"American Dental Association Health Foundation, Paffenbarger Research Center, Polymers Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Shih","sequence":"additional","affiliation":[{"name":"American Dental Association Health Foundation, Paffenbarger Research Center, Polymers Division, National Institute of Standards and Technology, Gaithersburg, Maryland 20899"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1992,3,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1177\/00220345900690S118"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1159\/000261198"},{"key":"atypb3","first-page":"338","volume":"70","author":"Carey, C.","year":"1991","journal-title":"JDent Res"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1159\/000261400"},{"key":"atypb5","first-page":"453","volume":"70","author":"Chow, L.C.","year":"1991","journal-title":"J Dent Res"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.6028\/jres.096.009"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1177\/00220345880670081201"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1159\/000261262"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1159\/000260936"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1159\/000261133"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1159\/000260937"},{"key":"atypb12","first-page":"230","volume":"6","author":"Mallon, D.E.","year":"1984","journal-title":"Pediatric Dent"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1159\/000260637"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1177\/00220345850640030401"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1159\/000261139"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1159\/000261218"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1177\/00220345900690060701"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1177\/00220345900690S120"},{"key":"atypb19","unstructured":"Ten Cate, J.M. and Simons, Y.M. (1986): The Efficacyof Toothpaste with Different Fluoride Contents, a pH-cycling Study. In: Factors Relating to Demineralisation and Remineralisation of the Teeth, S.A. Leach, Ed. Oxford: IRL Press , p. 35."},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1159\/000261078"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1159\/000261035"},{"key":"atypb22","first-page":"340","volume":"70","author":"Vogel, G.","year":"1991","journal-title":"JDent Res"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1177\/00220345900690S122"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1159\/000261013"},{"key":"atypb25","first-page":"26","volume":"22","author":"White, D.J.","year":"1988","journal-title":"F Distribution, Surface Hardening and Remineralization, Caries Res"},{"key":"atypb26","doi-asserted-by":"publisher","DOI":"10.1159\/000261059"}],"container-title":["Journal of Dental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00220345920710030401","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00220345920710030401","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T21:02:44Z","timestamp":1777496564000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00220345920710030401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,3]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1992,3]]}},"alternative-id":["10.1177\/00220345920710030401"],"URL":"https:\/\/doi.org\/10.1177\/00220345920710030401","relation":{},"ISSN":["0022-0345","1544-0591"],"issn-type":[{"value":"0022-0345","type":"print"},{"value":"1544-0591","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,3]]}}}