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Plaque accumulation (Plaque Index) and gingival inflammation (Gingival Index) were recorded at one, two, four, six, and eight weeks. The local delivery of low-dose chlorhexidine to dogs significantly inhibited gingivitis and plaque formation. It is concluded that the dental application of a film-forming system may be a preferable method of periodontal disease prophylaxis, and may enhance supragingival plaque control in areas of isolated periodontal problems associated with obvious local predisposing factors.<\/jats:p>","DOI":"10.1177\/00220345920710090601","type":"journal-article","created":{"date-parts":[[2010,11,28]],"date-time":"2010-11-28T21:14:56Z","timestamp":1290978896000},"page":"1577-1581","source":"Crossref","is-referenced-by-count":11,"title":["Inhibition of Plaque Formation and Gingivitis in Beagle Dogs by Topical Use of a Degradable Controlled-release System Containing Chlorhexidine"],"prefix":"10.1177","volume":"71","author":[{"given":"A.","family":"Kozlovsky","sequence":"first","affiliation":[{"name":"Department of Periodontology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv 69978, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Sintov","sequence":"additional","affiliation":[{"name":"Perio Products Ltd., POB 23950, Jerusalem 91237, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Zubery","sequence":"additional","affiliation":[{"name":"Department of Periodontology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv 69978, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Tal","sequence":"additional","affiliation":[{"name":"Department of Periodontology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv 69978, Israel"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1992,9,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1986.tb01434.x"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1983.tb01268.x"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1974.tb01248.x"},{"key":"atypb4","first-page":"23","volume":"10","author":"Brayer L.","year":"1988","journal-title":"Clin Prev Dent"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1984.tb00908.x"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1988.tb01025.x"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1973.tb02167.x"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1970.tb00699.x"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1973.tb02162.x"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1982.tb01160.x"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1159\/000260145"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(74)90090-9"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1980.tb02150.x"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1988.tb01595.x"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1989.60.3.127"},{"key":"atypb16","first-page":"5","volume":"16","author":"Kornman KS","year":"1986","journal-title":"A review of current concepts. 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