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The aim of this study was to characterize the enamel of teeth from patients suffering from recessive epidermolysis bullosa dystrophica (rEBD) in terms of its mineral content, carbonate content, protein content, and amino acid composition. The results showed that dental enamel from these patients was essentially normal in terms of its chemistry. It is therefore concluded that the high caries experience in recessive dystrophic epidermolysis bullosa patients is probably related to other factors, such as compromised oral hygiene and prolonged oral clearance due to extensive oral soft tissue damage and a cariogenic diet.<\/jats:p>","DOI":"10.1177\/00220345960750090901","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T19:39:42Z","timestamp":1231443582000},"page":"1672-1678","source":"Crossref","is-referenced-by-count":19,"title":["The Chemical Composition of Tooth Enamel in Recessive Dystrophic Epidermolysis Bullosa: Significance with Respect to Dental Caries"],"prefix":"10.1177","volume":"75","author":[{"given":"J.","family":"Kirkham","sequence":"first","affiliation":[{"name":"to whom correspondence should be addressed"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Robinson","sequence":"additional","affiliation":[{"name":"Division of Oral Biology, Leeds Dental Institute, Clarendon Way, Leeds, LS2 9LU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.M.","family":"Strafford","sequence":"additional","affiliation":[{"name":"Division of Oral Biology, Leeds Dental Institute, Clarendon Way, Leeds, LS2 9LU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.C.","family":"Shore","sequence":"additional","affiliation":[{"name":"Division of Oral Biology, Leeds Dental Institute, Clarendon Way, Leeds, LS2 9LU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.A.","family":"Bonass","sequence":"additional","affiliation":[{"name":"Division of Oral Biology, Leeds Dental Institute, Clarendon Way, Leeds, LS2 9LU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.J.","family":"Brookes","sequence":"additional","affiliation":[{"name":"Division of Oral Biology, Leeds Dental Institute, Clarendon Way, Leeds, LS2 9LU, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.T.","family":"Wright","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1996,9,1]]},"reference":[{"key":"atypb1","volume-title":"Investigation into the microstructure and micro-chemistry of enamel of deciduous teeth (PhD thesis)","author":"Athanassoulis-Besbeas TM","year":"1968"},{"key":"atypb2","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/0003-9969(65)90126-3","volume":"10","author":"Bachra BN","year":"1965","journal-title":"Arch Oral Biol"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1988.01670050078026"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1126\/science.1720261"},{"key":"atypb5","first-page":"255","volume":"6","author":"Brain EB","year":"1968","journal-title":"Br Dent J 124(Pt"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(94)00135-X"},{"key":"atypb7","unstructured":"Bruckner-Tuderman L. 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