{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:16:52Z","timestamp":1792804612562,"version":"4.5.0"},"reference-count":32,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[1999,12,1]],"date-time":"1999-12-01T00:00:00Z","timestamp":944006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Dent Res"],"published-print":{"date-parts":[[1999,12]]},"abstract":"<jats:p>Dental erosion shows a typical distribution pattern within the dental arches. Tooth protection from erosion by salivary pellicle has been shown in vitro, but the hypothesis that pellicle may differ quantitatively at sites of erosion has not been investigated. This study aimed to determine the thickness of acquired salivary pellicle within the dental arches, investigate the possible relationship of this thickness to the distribution and severity of erosion within the arches, and confirm the protective effect of pellicle against dental erosion. Eight enamel blocks were produced from each of 5 bovine incisors assigned to five volunteers. Each block was further cut into 2 slabs, producing control and experimental slabs. Pellicle developed on experimental slabs located on 8 intra-oral sites after 1 hr of exposure was stained by \"sheep anti-human IgGAM-FITC\". Slabs were then visualized, and pellicle thickness measured, by confocal laser scanning microscopy. Eroded enamel lesions were produced in experimental and control slabs by means of pure orange juice. The degree of erosion was quantified by transverse microradiography. Pellicle thickness varied significantly within the dental arches and among individuals. An inverse relationship (r = -0.96, p &lt; 0.001) was observed between the degree of erosion and pellicle thickness. Significant differences in erosion were observed between slabs with and those without pellicle. This study has shown that the thickness of acquired salivary pellicle varies within the dental arches, which may be responsible for the site-specificity of dental erosion, and that pellicle does protect the teeth from erosion.<\/jats:p>","DOI":"10.1177\/00220345990780120901","type":"journal-article","created":{"date-parts":[[2009,1,8]],"date-time":"2009-01-08T19:39:42Z","timestamp":1231443582000},"page":"1821-1828","source":"Crossref","is-referenced-by-count":131,"title":["Thickness of Acquired Salivary Pellicle as a Determinant of the Sites of Dental Erosion"],"prefix":"10.1177","volume":"78","author":[{"given":"B.T.","family":"Amaechi","sequence":"first","affiliation":[{"name":"Cariology Research Group, Department of Clinical Dental Sciences, School of Dentistry, University of Liverpool, Liverpool, L69 3BX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.M.","family":"Higham","sequence":"additional","affiliation":[{"name":"Cariology Research Group, Department of Clinical Dental Sciences, School of Dentistry, University of Liverpool, Liverpool, L69 3BX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.M.","family":"Edgar","sequence":"additional","affiliation":[{"name":"Cariology Research Group, Department of Clinical Dental Sciences, School of Dentistry, University of Liverpool, Liverpool, L69 3BX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Milosevic","sequence":"additional","affiliation":[{"name":"Cariology Research Group, Department of Clinical Dental Sciences, School of Dentistry, University of Liverpool, Liverpool, L69 3BX, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1999,12,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1159\/000016471"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4809187"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.4809560"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(86)90837-8"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1159\/000016486"},{"key":"atypb6","first-page":"133","volume":"72","author":"Dawes C.","year":"1993","journal-title":"J Dent Res"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/32\/7\/008"},{"key":"atypb8","first-page":"683","volume":"68","journal-title":"Dent"},{"key":"atypb9","doi-asserted-by":"crossref","unstructured":"Fontana M, Gfell LE, Gregory RL (1995). Characterization of preparations enriched for Streptococcus mutans fimbriae: salivary immunoglobulin A antibodies in caries-free and caries-active subjects. Clin Diagn Lab Immunol 2:719-725. Gudmundsson K, Kristleifsson G, Theodors A, Holbrook WP (1995). Tooth erosion, gastroesophageal reflux, and salivary buffer capacity. Oral Surg Oral Med Oral Pathol 79:185-189. Hay DI (1967). The adsorption of salivary proteins by hydroxyapatite and enamel. 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Caries Res 21:353-359. Millward A, Shaw L, Smith A (1994a). Dental erosion in four-year-old children from differing socioeconomic backgrounds. 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Chemical composition of salivary integuments formed in vivo on solids with some established surface characteristics. Arch Oral Biol 20:687-691. Sonju T, Rolla G (1973). Chemical analysis of the acquired pellicle formed in two hours on cleaned human teeth in vivo. Rate of formation and amino acid analysis. Caries Res 7:30-38. Tabak LA, Levine MJ, Jain NK, Bryan AR, Cohen RE, Monte LD, et al. (1985). Adsorption of human salivary mucins to hydroxyapatite. Arch Oral Biol 30:423-427.","DOI":"10.1016\/0003-9969(75)90138-7"},{"key":"atypb31","doi-asserted-by":"crossref","unstructured":"Thomas AK (1957). Further observations on the influence of citrus fruit juices on human teeth. NY State Dent J 23:424-430. Veerman EC, Van den Keybus PA, Vissink A, Nieuw Amerongen AV (1996). Human glandular salivas: their separate collection and analysis. Eur J Oral Sci 104:346-352. Zahradnik RT, Moreno EC, Burke EJ (1976). Effect of salivary pellicle on enamel subsurface demineralization in vitro. 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