{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T00:51:01Z","timestamp":1792111861363,"version":"4.4.0"},"reference-count":31,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[1998,2,1]],"date-time":"1998-02-01T00:00:00Z","timestamp":886291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Histochem Cytochem."],"published-print":{"date-parts":[[1998,2]]},"abstract":"<jats:p>Immunolocalization studies demonstrate that Type VI collagen forms a flexible network that interweaves among collagen fibrils in the dermis of skin as well as in other loose connective tissues. Although binding of Type VI collagen with other matrix components has been suggested, no structural evidence supporting these studies has been reported. In this study, we demonstrate that Type VI microfilaments consistently cross-banded collagen fibrils near the \u201cd\u201d band, indicating that the interaction of Type VI collagen with banded fibrils is not passive. This \u201cd\u201d band is also the location of the binding domain of decorin to banded fibrils, suggesting that decorin mediates the interaction of Type VI microfilaments with banded fibers. Examination of the architecture of the Type VI network in a decorin nullizygous mouse demonstrates a continuance of this specific interaction, indicating that the association is not entirely dependent on the presence of decorin. At least one other component, whose identity is uncertain, persists near the \u201cd\u201d band, which may also serve to mediate the attachment of Type VI collagen to collagen fibrils.<\/jats:p>","DOI":"10.1177\/002215549804600210","type":"journal-article","created":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T03:11:07Z","timestamp":1301627467000},"page":"215-220","source":"Crossref","is-referenced-by-count":35,"title":["Type VI Microfilaments Interact with a Specific Region of Banded Collagen Fibrils in Skin"],"prefix":"10.1177","volume":"46","author":[{"given":"Douglas R.","family":"Keene","sequence":"first","affiliation":[{"name":"Shriners Hospital for Children, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine C.","family":"Ridgway","sequence":"additional","affiliation":[{"name":"Shriners Hospital for Children, Portland, Oregon"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renato V.","family":"Iozzo","sequence":"additional","affiliation":[{"name":"Department of Pathology, Anatomy, and Cell Biology, and the Kimmel Cancer Center, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[1998,2,1]]},"reference":[{"key":"bibr1-002215549804600210","doi-asserted-by":"crossref","first-page":"5250","DOI":"10.1016\/S0021-9258(18)42759-7","volume":"267","author":"Bidanset DJ","year":"1992","journal-title":"J Biol Chem"},{"key":"bibr2-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1016\/S0934-8832(11)80016-8"},{"key":"bibr3-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.103.2.393"},{"key":"bibr4-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.136.3.729"},{"key":"bibr5-002215549804600210","doi-asserted-by":"crossref","first-page":"4571","DOI":"10.1016\/S0021-9258(18)83781-4","volume":"264","author":"Fisher LW","year":"1989","journal-title":"J Biol Chem"},{"key":"bibr6-002215549804600210","doi-asserted-by":"publisher","DOI":"10.3109\/17453679509157649"},{"key":"bibr7-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1016\/1047-8477(91)90065-5"},{"key":"bibr8-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1042\/bj2110303"},{"key":"bibr9-002215549804600210","doi-asserted-by":"crossref","first-page":"6898","DOI":"10.1016\/S0021-9258(18)83516-5","volume":"264","author":"Hedbom E","year":"1989","journal-title":"J Biol Chem"},{"key":"bibr10-002215549804600210","doi-asserted-by":"crossref","first-page":"27307","DOI":"10.1016\/S0021-9258(19)74250-1","volume":"268","author":"Hedbom E","year":"1993","journal-title":"J Biol Chem"},{"key":"bibr11-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.3.9.2663581"},{"key":"bibr12-002215549804600210","first-page":"189","volume-title":"Connective Tissue and Its Heritable Disorders.","author":"Heineg\u00e5rd D","year":"1993"},{"key":"bibr13-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1177\/31.6.6341460"},{"key":"bibr14-002215549804600210","doi-asserted-by":"publisher","DOI":"10.3109\/10409239709108551"},{"key":"bibr15-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.10.5.8621059"},{"key":"bibr16-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.107.5.1995"},{"key":"bibr17-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0029(19970815)38:4<394::AID-JEMT7>3.0.CO;2-J"},{"key":"bibr18-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1021\/bi00435a020"},{"key":"bibr19-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1995.tb20820.x"},{"key":"bibr20-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.83.20.7683"},{"key":"bibr21-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-5155(97)00011-7"},{"key":"bibr22-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.32.19578"},{"key":"bibr23-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.1070280505"},{"key":"bibr24-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1016\/0076-6879(94)45004-8"},{"key":"bibr25-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1042\/bj2520313"},{"key":"bibr26-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1021\/bi960773t"},{"key":"bibr27-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.6.2776"},{"key":"bibr28-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1016\/S0934-8832(89)80006-X"},{"key":"bibr29-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1177\/41.10.8245404"},{"key":"bibr30-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1042\/bj2230587"},{"key":"bibr31-002215549804600210","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.50.31767"}],"container-title":["Journal of Histochemistry &amp; 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