{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,3]],"date-time":"2026-05-03T23:43:56Z","timestamp":1777851836003,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[1999,7,1]],"date-time":"1999-07-01T00:00:00Z","timestamp":930787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Histochem Cytochem."],"published-print":{"date-parts":[[1999,7]]},"abstract":"<jats:p>We have investigated by immunochemistry the distribution of H Type 3\/4 chains of the ABO histo-blood group system in human submandibular gland using a monoclonal anti-H MBr1 antibody specific for H Type 3\/4 chains, and have found the expression of H Type 3\/4 chains was mainly in the serous cells. Serous cells from secretors were stained by MBr1 but not by anti-A and anti-B antibodies, whereas serous cells from nonsecretors exhibited a negative reaction with MBr1. Mucous cells were not stained by MBr1. Only a few striated duct cells showed a weak reaction with anti-H MBr1. These results suggested that the H Type 3\/4 chains were distributed predominantly in the serous cells of the human submandibular gland and that secretor Type \u03b1 (1,2) fucosyltransferase (Se enzyme) controlled the synthesis of H Type 3\/4 chains in vivo. Saliva also contained H Type 3\/4 chains, which were controlled by the secretor gene ( FUT2). The differences in the distributions of H Type 1, H Type 2, and H Type 3\/4 chains of the ABO histo blood group system in the submandibular gland are discussed.<\/jats:p>","DOI":"10.1177\/002215549904700706","type":"journal-article","created":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T03:11:07Z","timestamp":1301627467000},"page":"889-894","source":"Crossref","is-referenced-by-count":9,"title":["Presence of H Type 3\/4 Chains of ABO Histo-blood Group System in Serous Cells of Human Submandibular Gland and Regulation of Their Expression by the Secretor Gene (\n                    <i>FUT2<\/i>\n                    )"],"prefix":"10.1177","volume":"47","author":[{"given":"Yuhua","family":"Liu","sequence":"first","affiliation":[{"name":"Division of Human Genetics, Department of Forensic Medicine, Kurume University School of Medicine, Kurume, 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