{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:48:37Z","timestamp":1790704117380,"version":"4.1.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T00:00:00Z","timestamp":1390521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lab Anim"],"published-print":{"date-parts":[[2014,4]]},"abstract":"<jats:p>\n                    Eighteen female New Zealand White rabbits (3.9\u2009\u00b1\u20090.4\u2009kg) were anaesthetized with sufentanil\u2013midazolam by intravenous infusion (SUF\u2013MID, n\u2009=\u20099) or isoflurane (ISO, n\u2009=\u20099) for bilateral creation of an osteochondral defect in the medial femur condyle. Subcutaneous premedication with 0.1\u2009mg\/kg medetomidine and anaesthesia induction by intravenous infusion of 1.1\u2009\u00b5g\/kg sufentanil and 0.2\u2009mg\/kg midazolam were identical in both groups. During surgery (60\u2009min), the effects on respiratory and circulatory variables serum lactate, total protein and blood glucose were examined. Intermittent positive pressure ventilation (IPPV) was initiated if apnoea lasted&gt;30\u2009s or if end-tidal CO\n                    <jats:sub>2<\/jats:sub>\n                    \u22658\u2009kPa. The righting reflex was lost in 3\u2009min. IPPV was necessary during most of the anaesthesia for most of the rabbits. Maintenance doses during surgery were 2.0\u2009\u00b5g\/kg\/h sufentanil and 0.4\u2009mg\/kg\/h midazolam, and 1.4% isoflurane, respectively. Mean arterial blood pressure (MAP) was higher in group SUF\u2013MID than group ISO during surgery (63\u2009\u00b1\u200912 vs 50\u2009\u00b1\u20098\u2009mmHg). In group ISO the heart rate was higher during surgery than before anaesthesia (197\u2009\u00b1\u200926 vs 158\u2009\u00b1\u200940 bpm) as was blood glucose (9\u2009\u00b1\u20092 vs 12\u2009\u00b1\u20093\u2009mmol\/L). Serum lactate levels remained unchanged whereas total protein decreased in both groups. Time to recover from anaesthesia did not differ between groups (20\u2009min). Intravenous sufentanil\u2013midazolam infusion provided surgical anaesthesia with a higher MAP than isoflurane anaesthesia. The protocol can be useful in situations in which gas anaesthesia cannot be used or in animals with limited cardiovascular reserves. However, IPPV is necessary.\n                  <\/jats:p>","DOI":"10.1177\/0023677213516311","type":"journal-article","created":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T22:31:36Z","timestamp":1390602696000},"page":"155-163","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Anaesthesia in medetomidine premedicated New Zealand White rabbits: a comparison between intravenous sufentanil\u2013midazolam and isoflurane anaesthesia for orthopaedic surgery"],"prefix":"10.1177","volume":"48","author":[{"given":"Patricia","family":"Hedenqvist","sequence":"first","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Edner","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Jensen-Waern","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences, Uppsala, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,1,24]]},"reference":[{"key":"bibr1-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2009.02.001"},{"key":"bibr2-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(00)00132-0"},{"key":"bibr3-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2008.00397.x"},{"key":"bibr4-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1258\/la.2008.007152"},{"key":"bibr5-0023677213516311","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.2460\/ajvr.1999.60.10.1189","volume":"60","author":"Imai A","year":"1999","journal-title":"Am J Vet Res"},{"key":"bibr6-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1136\/vr.164.26.803"},{"key":"bibr7-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.2011.00685.x"},{"key":"bibr8-0023677213516311","volume-title":"Laboratory animal anaesthesia. An introduction for research workers and technicians","author":"Flecknell PA","year":"1987"},{"key":"bibr9-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/61.2.194"},{"key":"bibr10-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198708000-00003"},{"key":"bibr11-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000064202.24119.07"},{"key":"bibr12-0023677213516311","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.2460\/ajvr.1987.48.09.1372","volume":"48","author":"Benson GJ","year":"1987","journal-title":"Am J Vet Res"},{"key":"bibr13-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-2995.1991.tb00544.x"},{"key":"bibr14-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1152\/jn.01043.2003"},{"key":"bibr15-0023677213516311","doi-asserted-by":"publisher","DOI":"10.3109\/08941939409018289"},{"key":"bibr16-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-198412000-00018"},{"key":"bibr17-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1007\/BF03007455"},{"key":"bibr18-0023677213516311","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-198836030-00003"},{"key":"bibr19-0023677213516311","first-page":"362","volume":"72","author":"Garofalo NA","year":"2008","journal-title":"Can J Vet Res"},{"key":"bibr20-0023677213516311","first-page":"9","volume":"28","author":"Hedenqvist P","year":"2013","journal-title":"BMC Vet Res"},{"key":"bibr21-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2012.02.575"},{"key":"bibr22-0023677213516311","doi-asserted-by":"publisher","DOI":"10.1258\/0023677021911740"},{"key":"bibr23-0023677213516311","doi-asserted-by":"crossref","unstructured":"Swindle MM, Schumann RE, Johnson WS, et\u00a0al. High dose narcotic anesthesia using sufentanil in swine and dogs. In:\n                      Proceedings of the 4th International Conference of Veterinary Anesthesia\n                      (ed LW Hall), Utrecht, The Netherlands.\n                      J Vet Anaesth (Special Supplement)\n                      1991:273\u2013276.","DOI":"10.1111\/j.1467-2995.1991.tb00562.x"},{"key":"bibr24-0023677213516311","first-page":"270","volume":"40","author":"Borkowski GL","year":"1990","journal-title":"Lab Anim Sci"},{"key":"bibr25-0023677213516311","first-page":"574","volume":"78","author":"Kadoi Y","year":"2012","journal-title":"Minerva Anestesiol"},{"key":"bibr26-0023677213516311","first-page":"32","volume":"46","author":"Morgan TJ","year":"2007","journal-title":"J Am Assoc Lab Anim Sci"},{"key":"bibr27-0023677213516311","first-page":"166","volume":"48","author":"Stephens Devalle JM","year":"2009","journal-title":"J Am Assoc Lab Anim Sci"}],"container-title":["Laboratory Animals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0023677213516311","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0023677213516311","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0023677213516311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T07:33:55Z","timestamp":1777620835000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0023677213516311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,24]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1177\/0023677213516311"],"URL":"https:\/\/doi.org\/10.1177\/0023677213516311","relation":{},"ISSN":["0023-6772","1758-1117"],"issn-type":[{"value":"0023-6772","type":"print"},{"value":"1758-1117","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,24]]}}}