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The drug can be easily and safely administered using drinking water. This simple regimen should control pinworm infection ( Syphacia muris), a problem that can be endemic in laboratory colonies. Experiments using healthy animals are likely to generate more consistent results, thereby requiring a reduced number of animals per group.<\/jats:p>","DOI":"10.1177\/0023677214562850","type":"journal-article","created":{"date-parts":[[2014,12,5]],"date-time":"2014-12-05T21:33:31Z","timestamp":1417815211000},"page":"196-200","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":14,"title":["Efficacy and security of ivermectin given orally to rats naturally infected with\n                    <i>Syphacia<\/i>\n                    spp.,\n                    <i>Giardia<\/i>\n                    spp. and\n                    <i>Hymenolepis nana<\/i>"],"prefix":"10.1177","volume":"49","author":[{"given":"VRS","family":"Foletto","sequence":"first","affiliation":[{"name":"Department of Pharmacology, Federal University of Santa Catarina, Florian\u00f3polis, Santa Catarina, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F","family":"Vanz","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Federal University of Santa Catarina, Florian\u00f3polis, Santa Catarina, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Gazarini","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Federal University of Santa Catarina, Florian\u00f3polis, Santa Catarina, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CAJ","family":"Stern","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Federal University of Santa Catarina, Florian\u00f3polis, Santa Catarina, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"CR","family":"Tonussi","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Federal University of Santa Catarina, Florian\u00f3polis, Santa Catarina, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2014,12,5]]},"reference":[{"key":"bibr1-0023677214562850","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/942616"},{"key":"bibr2-0023677214562850","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.11.2.231"},{"key":"bibr3-0023677214562850","doi-asserted-by":"publisher","DOI":"10.1258\/002367794780745263"},{"key":"bibr4-0023677214562850","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-263620-2.50029-X"},{"key":"bibr5-0023677214562850","first-page":"391","volume":"29","author":"Pearson DJ","year":"1975","journal-title":"Immunology"},{"key":"bibr6-0023677214562850","unstructured":"Lindsey J, Boorman G, Colins M, Infectious diseases of mice and rats\n                      (Committee of Infectious Diseases of Mice and Rats)\n                      , Washington: National Academic Press, 1991, pp. 275\u2013276."},{"key":"bibr7-0023677214562850","first-page":"219","volume-title":"Manual of microbiologic monitoring of laboratory animals","author":"Farrar PL","year":"1994","edition":"2"},{"key":"bibr8-0023677214562850","first-page":"191","volume-title":"Manual of microbiologic monitoring of laboratory animals","author":"Potkay S","year":"1994","edition":"2"},{"key":"bibr9-0023677214562850","doi-asserted-by":"publisher","DOI":"10.1002\/9780470344552.ch11"},{"key":"bibr10-0023677214562850","doi-asserted-by":"publisher","DOI":"10.1258\/002367776780948862"},{"key":"bibr11-0023677214562850","doi-asserted-by":"publisher","DOI":"10.1007\/BF01308343"},{"key":"bibr12-0023677214562850","doi-asserted-by":"publisher","DOI":"10.1258\/002367781780958982"},{"key":"bibr13-0023677214562850","first-page":"476","volume":"38","author":"Wagner M","year":"1988","journal-title":"Lab Anim Sci"},{"key":"bibr14-0023677214562850","first-page":"461","volume":"39","author":"Flynn BM","year":"1989","journal-title":"Lab Anim Sci"},{"key":"bibr15-0023677214562850","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(76)80097-2"},{"key":"bibr16-0023677214562850","first-page":"279","volume-title":"CRC handbook series in zoonoses. 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