{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T08:24:18Z","timestamp":1787300658717,"version":"build-2736575974"},"reference-count":23,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lab Anim"],"abstract":"<jats:p>\n                    A five-week-old female B6.129S4-\n                    <jats:italic toggle=\"yes\">\n                      C3\n                      <jats:sup>tm1Crr<\/jats:sup>\n                    <\/jats:italic>\n                    \/J (C3 knockout) mouse presented with abdominal distension and reduced general condition. The animal was euthanized and submitted for necropsy. Gross examination revealed marked dilation of the left kidney and ureter, both containing clear fluid consistent with urine and a focal rupture of the renal capsule with associated uroabdomen. Histopathological evaluation revealed multicystic renal dysplasia characterized by immature glomeruli, primitive tubules, persistent mesenchyme, and dilated collecting ducts, accompanied by a tortuous and dilated ureter. In addition, chronic arteritis was identified in a medium-sized artery within the affected kidney.\n                  <\/jats:p>","DOI":"10.1177\/00236772261469961","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T12:20:46Z","timestamp":1786969246000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Multicystic renal dysplasia with ureteral anomaly and arteritis in a C3-deficient mouse"],"prefix":"10.1177","author":[{"given":"Dhanushka","family":"Hewapathirana","sequence":"first","affiliation":[{"name":"Institute of Animal Pathology, University of Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3052-8802","authenticated-orcid":false,"given":"Christine","family":"Goepfert","sequence":"additional","affiliation":[{"name":"Institute of Animal Pathology, University of Bern, Switzerland"},{"name":"MultiOmics Histology Core Facility, \u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,8,17]]},"reference":[{"key":"e_1_3_3_2_2","volume-title":"Jubb, Kennedy, and Palmer\u2019s pathology of domestic animals: Volume 2","author":"Maxie G.","year":"2025","unstructured":"Maxie G. 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