{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T09:09:40Z","timestamp":1789808980788,"version":"4.0.1"},"reference-count":109,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T00:00:00Z","timestamp":1789516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100000038","name":"natural sciences and engineering research council of canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Lab Anim"],"abstract":"<jats:p>\n                    This invited perspective imagines 2066, this journal\u2019s centennial. Building on current understandings of rodent cognition, affect and welfare needs, we envision a world with dramatically altered societal attitudes toward rats and mice: widely kept as companion animals (pets), they are valued as intelligent, sociable beings. Scientific validity, animal welfare and human welfare are also considered inseparable priorities, further transforming biomedical animal-use. Within this context, animal-based research now involves two complementary models. Laboratory research persists, under conditions radically improved over today\u2019s: environments are large, naturalistic and highly \u2018enriched\u2019; and procedures rely on voluntary participation (ruling out any that animals will not tolerate). In addition, \u2018research clinics\u2019 operate, where naturally sick or ageing companion rodents are patients in clinical trials that integrate research with veterinary care. Now the only way to study harms like cancer and pain (or to use invasive procedures, if animals\u2019 guardians\u2019 consent), these trials benefit animals\n                    <jats:italic toggle=\"yes\">and<\/jats:italic>\n                    generate data with improved translational relevance. In both systems, high welfare conditions across rodents\u2019 lifespans \u2013 from prenatal care to end-of-natural-life euthanasia \u2013 produce resilient, robust individuals whose excellent well-being and stable physiologies enhance replicability and translational success. Care staff and researcher well-being is also improved by positive human\u2013animal interactions, pleasant environments, and enhanced societal regard for animal-based biomedical research. Although intentionally idealistic, we contend that meaningful progress\n                    <jats:italic toggle=\"yes\">needs<\/jats:italic>\n                    this reimagining of research approaches and human\u2013animal relationships: that the proposed changes are essential for tackling today\u2019s pressing problems in animal-based biomedical science. We invite this journal\u2019s community to envisage how to realise such a future.\n                  <\/jats:p>","DOI":"10.1177\/00236772261475086","type":"journal-article","created":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T04:26:46Z","timestamp":1789619206000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A future \u2018rodentopia\u2019? Imagining a good life for rats and mice used in research (and the humans who work with them)"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8045-4579","authenticated-orcid":false,"given":"Georgia","family":"Mason","sequence":"first","affiliation":[{"name":"Campbell Centre for the Study of Animal Welfare\/Integrative Biology Department, University of Guelph, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Weary","sequence":"additional","affiliation":[{"name":"Animal Welfare Programme, Faculty of Land and Food Systems, University of British Columbia, Vancouver, BC, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1037\/a0027355","article-title":"Covariation of learning and \u201creasoning\u201d abilities in mice: evolutionary conservation of the operations of intelligence","volume":"38","author":"Wass C","year":"2012","unstructured":"Wass C, Denman-Brice A, Rios C, et al. 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