{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:04:45Z","timestamp":1777896285438,"version":"3.51.4"},"reference-count":9,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1989,7,1]],"date-time":"1989-07-01T00:00:00Z","timestamp":615254400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Sci Law"],"published-print":{"date-parts":[[1989,7]]},"abstract":"<jats:p>\n                    A simple and rapid method for isolation of nine barbiturates with Sep-Pak C\n                    <jats:sub>18<\/jats:sub>\n                    cartridges from human urine, plasma and whole blood, is presented; the detection of drugs was made by wide-bore capillary gas chromatography (GC) with flame ionization. The drug-containing samples, after mixing with dilute acid solution, were directly applied to the cartridges and eluted with either chloroform\/methanol (9:1) or acetonitrile. Separation of the nine drugs was satisfactory with use of an intermediately polar HP-17 capillary column. Recoveries of most compounds were excellent for both chloroform\/methanol and acetonitrile as elution solvents. However, backgrounds were cleaner and evaporation time was much shorter for the chloroform\/methanol system. The present isolation method with use of Sep-Pak C\n                    <jats:sub>18<\/jats:sub>\n                    cartridges and wide-bore capillary GC seem very useful in the fields of forensic chemistry, clinical toxicology and clinical pharmacology.\n                  <\/jats:p>","DOI":"10.1177\/002580248902900309","type":"journal-article","created":{"date-parts":[[2017,1,21]],"date-time":"2017-01-21T05:21:45Z","timestamp":1484976105000},"page":"242-248","source":"Crossref","is-referenced-by-count":35,"title":["Rapid Isolation with Sep-Pak C\n                    <sub>18<\/sub>\n                    Cartridges and Wide-Bore Capillary Gas Chromatography of Some Barbiturates"],"prefix":"10.1177","volume":"29","author":[{"given":"O.","family":"Suzuki","sequence":"first","affiliation":[{"name":"Department of Legal Medicine, Hamamatsu University School of Medicine, Hamamatsu 431-31, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Kumazawa","sequence":"additional","affiliation":[{"name":"Department of Legal Medicine, Hamamatsu University School of Medicine, Hamamatsu 431-31, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Seno","sequence":"additional","affiliation":[{"name":"Department of Legal Medicine, Hamamatsu University School of Medicine, Hamamatsu 431-31, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Hattori","sequence":"additional","affiliation":[{"name":"Department of Legal Medicine, Aichi Medical University, Aichi 480-11, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1989,7,1]]},"reference":[{"key":"bibr1-002580248902900309","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4347(87)80185-8"},{"key":"bibr2-002580248902900309","first-page":"142","volume":"20","author":"Chiarotti M.","year":"1982","journal-title":"Acta Med. Rom."},{"key":"bibr3-002580248902900309","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)87024-2"},{"key":"bibr4-002580248902900309","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/27.1.198a"},{"key":"bibr5-002580248902900309","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(00)85115-4"},{"key":"bibr6-002580248902900309","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(00)83456-8"},{"key":"bibr7-002580248902900309","first-page":"325","volume":"39","author":"Majl\u00e0t P.","year":"1984","journal-title":"Pharmazie"},{"key":"bibr8-002580248902900309","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(00)96423-9"},{"key":"bibr9-002580248902900309","doi-asserted-by":"publisher","DOI":"10.1093\/jat\/7.4.178"}],"container-title":["Medicine, Science and the Law"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/002580248902900309","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/002580248902900309","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T08:14:55Z","timestamp":1777623295000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/002580248902900309"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,7]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1989,7]]}},"alternative-id":["10.1177\/002580248902900309"],"URL":"https:\/\/doi.org\/10.1177\/002580248902900309","relation":{},"ISSN":["0025-8024","2042-1818"],"issn-type":[{"value":"0025-8024","type":"print"},{"value":"2042-1818","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,7]]}}}