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Often a natural but sudden death is not subject to an autopsy, but only to an external examination, and this runs the risk of wrongly attributing the death to a cardiac cause. The present review is a retrospective-observational study which looks into the cases of sudden non-cardiac death recorded in the Genoa District (Italy) from 2014 to 2019 and investigated through complete autopsy examinations. Amongst these cases, 39 (31.5%) were attributable to gastrointestinal diseases, mostly due to the rupture of oesophageal varices; 39 (31.5%) to respiratory diseases, especially pulmonary infections; 31 (25%) to peripheral vascular disease, mostly attributable to pulmonary thromboembolisms or the acute dissection of aneurysms whilst the remaining 15 cases (12%) were attributable to intracranial haemorrhages.<\/jats:p>","DOI":"10.1177\/00258172211010547","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T04:08:09Z","timestamp":1622779689000},"page":"180-186","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Sudden unexpected non-cardiac death in the Genoa Medico-Legal District: A six year study (2014\u20132019) and literature review"],"prefix":"10.1177","volume":"89","author":[{"given":"Martina","family":"Drommi","sequence":"first","affiliation":[{"name":"Department of Forensic and Legal Medicine, University of Genova, Genova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Errico","sequence":"additional","affiliation":[{"name":"Department of Forensic and Legal Medicine, University of Genova, Genova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Barioglio","sequence":"additional","affiliation":[{"name":"Department of Forensic and Legal Medicine, University of Genova, Genova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Barranco","sequence":"additional","affiliation":[{"name":"Department of Forensic and Legal Medicine, University of Genova, Genova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Ventura","sequence":"additional","affiliation":[{"name":"Department of Forensic and Legal Medicine, University of Genova, Genova, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,6,4]]},"reference":[{"key":"bibr1-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1177\/002580240204200306"},{"key":"bibr2-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/j.mpdhp.2019.08.001"},{"key":"bibr3-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2004.12.024"},{"key":"bibr4-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2015.01.024"},{"key":"bibr5-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/S0379-0738(03)00212-3"},{"key":"bibr6-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1097\/PAF.0b013e3181c2dc96"},{"key":"bibr7-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(82)90552-X"},{"key":"bibr8-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/0046-8177(94)90094-9"},{"key":"bibr9-00258172211010547","first-page":"183","volume":"103","author":"Downes MR","year":"2010","journal-title":"Ir Med"},{"key":"bibr10-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.21.2849"},{"key":"bibr11-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-014-3252-5"},{"key":"bibr12-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1007\/s12024-009-9099-3"},{"key":"bibr13-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.2016.1157470"},{"key":"bibr14-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1186\/s12890-015-0033-z"},{"key":"bibr15-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1177\/0025802417737001"},{"key":"bibr16-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1054\/jcfm.2001.0497"},{"key":"bibr17-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1186\/1746-1596-2-27"},{"key":"bibr18-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-016-1401-8"},{"key":"bibr19-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/j.jflm.2015.10.004"},{"key":"bibr20-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/j.jflm.2015.02.005"},{"key":"bibr21-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.297.6661.1453"},{"key":"bibr22-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2009.04.009"},{"key":"bibr23-00258172211010547","doi-asserted-by":"publisher","DOI":"10.4103\/0377-4929.77323"},{"key":"bibr24-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1177\/002580249703700309"},{"key":"bibr25-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/j.forsciint.2013.08.008"},{"key":"bibr26-00258172211010547","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)80065-X"},{"key":"bibr27-00258172211010547","first-page":"384","volume":"34","author":"Sun ZC","year":"2018","journal-title":"Fa Yi Xue Za Zhi"},{"key":"bibr28-00258172211010547","unstructured":"ISTAT. 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