{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:09:01Z","timestamp":1777896541514,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T00:00:00Z","timestamp":1761523200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Med Leg J"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:p>\n                    We report a fatal case of\n                    <jats:italic toggle=\"yes\">Ammi visnaga<\/jats:italic>\n                    poisoning at Tangier\u2019s Forensic Medicine Department.\n                  <\/jats:p>\n                  <jats:p>\n                    An 18-year-old woman self-medicated with\n                    <jats:italic toggle=\"yes\">Ammi visnaga<\/jats:italic>\n                    powder to treat her vitiligo. She experienced a wide range of symptoms and rapid clinical deterioration with a fatal outcome. The autopsy revealed lesions consistent with cutaneous vitiligo, necrosis of the liver, kidneys, lungs and pancreas. Toxicological and histological analysis confirmed chronic inflammation and acute systemic damage, highlighting\n                    <jats:italic toggle=\"yes\">Ammi visnaga<\/jats:italic>\n                    \u2019s potential toxicity. Its bioactive components vary, with the toxic dose estimated at 1\u2009g per kg. This case demonstrates that prolonged consumption of herbal remedies like\n                    <jats:italic toggle=\"yes\">Ammi visnaga<\/jats:italic>\n                    can be dangerous and indeed fatal. Raising public awareness on the dangers of self-medication and need for medical supervision and education on the dosage and side effects of\n                    <jats:italic toggle=\"yes\">Ammi visnaga<\/jats:italic>\n                    is essential. The marketing of these products by non-professionals should be restricted.\n                  <\/jats:p>","DOI":"10.1177\/00258172251337046","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T04:06:42Z","timestamp":1761624402000},"page":"60-64","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Autopsy case: Vitiligo death from self-medication by\n                    <i>Ammi visnaga<\/i>\n                    poisoning"],"prefix":"10.1177","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0481-6811","authenticated-orcid":false,"given":"Rabi\u2019a","family":"Benyousef","sequence":"first","affiliation":[{"name":"Abdelmalek Essaadi University Faculty of Medicine and Pharmacy, Tangier, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azeddine","family":"Essadi","sequence":"additional","affiliation":[{"name":"Abdelmalek Essaadi University Faculty of Medicine and Pharmacy, Tangier, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Badreddine","family":"Zarhouni","sequence":"additional","affiliation":[{"name":"Abdelmalek Essaadi University Faculty of Medicine and Pharmacy, Tangier, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-7428-2102","authenticated-orcid":false,"given":"Mohammed","family":"Ouali","sequence":"additional","affiliation":[{"name":"Abdelmalek Essaadi University Faculty of Medicine and Pharmacy, Tangier, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elias M","family":"Numbi","sequence":"additional","affiliation":[{"name":"Abdelmalek Essaadi University Faculty of Medicine and Pharmacy, Tangier, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jihad","family":"Aarab","sequence":"additional","affiliation":[{"name":"Abdelmalek Essaadi University Faculty of Medicine and Pharmacy, Tangier, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samir","family":"Nya","sequence":"additional","affiliation":[{"name":"Abdelmalek Essaadi University Faculty of Medicine and Pharmacy, Tangier, Morocco"},{"name":"Forensic Medicine Department, Mohammed VI University Hospital, Tangier, Morocco"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,10,27]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1021\/np040106y"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-962061"},{"key":"e_1_3_2_4_2","first-page":"257","article-title":"Chemical constituents and pharmacological activities of ammi majus and ammi visnaga. A review","volume":"3","author":"Al-Snafi AE.","year":"2013","unstructured":"Al-Snafi AE. Chemical constituents and pharmacological activities of ammi majus and ammi visnaga. A review. Int J Pharm 2013; 3: 257\u2013265.","journal-title":"Int J Pharm"},{"key":"e_1_3_2_5_2","first-page":"40","article-title":"Melanin biosynthesis inhibitory activity of compounds isolated from unused parts of Ammi visinaga","volume":"3","author":"Ashour A","year":"2013","unstructured":"Ashour A, El-Sharkawy S, Amer M, et\u00a0al. Melanin biosynthesis inhibitory activity of compounds isolated from unused parts of Ammi visinaga. J Cosmet Dermatol Sci Appl 2013; 3: 40\u201343.","journal-title":"J Cosmet Dermatol Sci Appl"},{"key":"e_1_3_2_6_2","first-page":"301","article-title":"Ammi visnaga L., a potential medicinal plant: A review","volume":"25","author":"Khalil N","year":"2020","unstructured":"Khalil N, Bishr M, Desouky S, et\u00a0al. Ammi visnaga L., a potential medicinal plant: A review. Mol Basel Switz 2020; 25: 301.","journal-title":"Mol Basel Switz"},{"key":"e_1_3_2_7_2","doi-asserted-by":"crossref","unstructured":"Ahmed SST Fahim J Abdelmohsen UR. Chemical and biological potential of Ammi visnaga (L.) Lam. and Apium graveolens L.: A review (1963\u20132020). J Adv Biomed Pharm Sci 2021; 4: 160\u2013176. DOI: 10.21608\/jabps.2021.55949.1115.","DOI":"10.21608\/jabps.2021.55949.1115"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/14786410310001608091"},{"key":"e_1_3_2_9_2","unstructured":"Asmae K Na\u00efma R Abderrahim C et al. Intoxication aux plantes. Les plantes et la sante publique Centre Anti-Poison et de Pharmacovigilance du Maroc. (2010 2 trimestre). Toxicologie Maroc (5). Rabat Maroc: Minist\u00e8re de la Sant\u00e9. 2010 p. 16."},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10298-015-0936-4"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.26452\/ijrps.v11iSPL4.4239"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.2478\/intox-2019-0004"},{"key":"e_1_3_2_13_2","doi-asserted-by":"crossref","unstructured":"Guba R. Toxicity myths: The actual risks of essential oil Use. Perfumer & Flavorist 2000; 25(2): 10\u201314.","DOI":"10.1016\/S0962-4562(00)80007-7"},{"key":"e_1_3_2_14_2","unstructured":"Kumar V Abbas AK Aster JC. Robbins & Cotran Pathologic basis of disease. 9th ed. Philadelphia: Elsevier Health Sciences 2014."},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2013.06.002"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(06)81564-5"}],"container-title":["Medico-Legal Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00258172251337046","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00258172251337046","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00258172251337046","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T08:29:55Z","timestamp":1777624195000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00258172251337046"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,27]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1177\/00258172251337046"],"URL":"https:\/\/doi.org\/10.1177\/00258172251337046","relation":{},"ISSN":["0025-8172","2042-1834"],"issn-type":[{"value":"0025-8172","type":"print"},{"value":"2042-1834","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,27]]}}}