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Our assessment of participants followed the biopsychosocial model. Body function and structure were represented by muscle strength and postural sway during sit-to-stand movement, which were assessed by manual muscle testing and kinetics analysis, respectively. The Gross Motor Function Measure and Pediatric Balance Scale depicted the activity component. In addition, we included these relevant contextual factors: age, Home Observation for Measurement of the Environment, family income, and maternal schooling. A correlation analysis verified a suspected association between biopsychosocial and postural sway variables. There were significant separated correlations between postural sway in the three phases of the sit-to-stand movement, and age, GMFM-88 dimension D, and muscle strength. Thus, postural control in sit-to-stand movement was related to biopsychosocial factors involving different life aspects of children and adolescents with DS, and these factors should be addressed in rehabilitation therapy intended to improve postural control among these individuals.<\/jats:p>","DOI":"10.1177\/00315125221133432","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T03:04:32Z","timestamp":1665543872000},"page":"386-402","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Biopsychosocial Factors Related to Postural Sway During Sit-to-Stand Movement in Children and Adolescents With Down Syndrome: A Cross-Sectional Study"],"prefix":"10.1177","volume":"130","author":[{"given":"Maria Fernanda","family":"Pauletti Oliveira","sequence":"first","affiliation":[{"name":"Federal University of S\u00e3o Carlos, Sao Carlos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Camila","family":"Resende G\u00e2mbaro Lima","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Carlos, Sao Carlos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia Let\u00edcia","family":"Pav\u00e3o","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Carlos, Sao Carlos, Brazil"},{"name":"Federal University of Paran\u00e1, Curitiba, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisele","family":"Moreira Pena","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Carlos, Sao Carlos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5854-5941","authenticated-orcid":false,"given":"Bruna Rom\u00e3o","family":"da Silva","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Carlos, Sao Carlos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Carolina","family":"de Campos","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Carlos, Sao Carlos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelci Adriana","family":"Cicuto Ferreira Rocha","sequence":"additional","affiliation":[{"name":"Federal University of S\u00e3o Carlos, Sao Carlos, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,10,12]]},"reference":[{"key":"bibr1-00315125221133432","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph18063086"},{"key":"bibr2-00315125221133432","doi-asserted-by":"publisher","DOI":"10.1590\/S0034-89102005000400014"},{"key":"bibr3-00315125221133432","doi-asserted-by":"publisher","DOI":"10.3109\/09638288.2014.895058"},{"key":"bibr4-00315125221133432","doi-asserted-by":"publisher","DOI":"10.12659\/MSMBR.910448"},{"key":"bibr5-00315125221133432","doi-asserted-by":"publisher","DOI":"10.1037\/0012-1649.20.2.315"},{"key":"bibr6-00315125221133432","doi-asserted-by":"publisher","DOI":"10.1080\/09638288.2020.1830439"},{"key":"bibr7-00315125221133432","volume-title":"Quantitative data analysis for social scientists. 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