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Using purported mechanisms of the development of suicidal thoughts and behaviors across nine theories as a guide, a series of meta-analyses (K = 191 studies,\n                    <jats:italic toggle=\"yes\">N<\/jats:italic>\n                    = 79,106) were conducted. Posttraumatic stress disorder had a moderate association with suicidal thoughts and behaviors. Defeat and entrapment had large associations with both posttraumatic stress disorder and suicidal thoughts and behaviors. Hopelessness, shame, guilt, anger, and negative cognitions about other people each had moderate associations with both posttraumatic stress disorder and suicidal thoughts and behaviors. Smaller but significant associations were observed for distress tolerance, aggression\/hostility, social connection, negative cognitions about the self, self-harm, and acquired capability for suicide. Significant heterogeneity was detected in the meta-analyses and explored quantitatively to examine reasons for heterogeneity. These findings are consolidated into a new framework, the CEASE Framework, reflecting changes in\n                    <jats:bold>C<\/jats:bold>\n                    ognitions,\n                    <jats:bold>E<\/jats:bold>\n                    motions,\n                    <jats:bold>A<\/jats:bold>\n                    ttention\/executive functioning\/memory,\n                    <jats:bold>S<\/jats:bold>\n                    ensations and perceptions, and\n                    <jats:bold>E<\/jats:bold>\n                    xtreme behaviors that may underlie the association between posttraumatic stress disorder and suicide risk.\n                  <\/jats:p>","DOI":"10.1177\/00332941251409167","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T17:54:00Z","timestamp":1767376440000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Explaining the Link Between PTSD and Suicide: A Meta-Analysis to Introduce the CEASE Framework"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0879-0110","authenticated-orcid":false,"given":"Lily A.","family":"Brown","sequence":"first","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqin","family":"Zhu","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marin","family":"Kautz","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica","family":"Weitz","sequence":"additional","affiliation":[{"name":"University of Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,2]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/08039488.2019.1655589"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0749-5978(91)90020-T"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2019.07.014"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/10538712.2019.1678543"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/10538712.2017.1280577"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/sltb.12480"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/10926771.2017.1350773"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2020.104357"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2019.104126"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1041610210001791"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/13811118.2012.695269"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1300\/J146v11n04_02"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2017.12.054"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40479-017-0063-7"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1943-278X.1980.tb00768.x"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10608-018-9892-y"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1037\/tra0000663"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1037\/0033-295X.97.1.90"},{"key":"e_1_3_5_21_1","volume-title":"Depression: Clinical, experimental, and theoretical aspects","author":"Beck A. 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