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This research aimed to know the repercussion of a psychosocial healthcare program with PEH using mobile phones. This quasi-experimental study previously and subsequently evaluated interventions with 30 users (Complete Intervention = 23; Partial Intervention = 7) at 3 and 6 months. They periodically attended two municipal shelters for PEH.. At 3 months, those who did the complete intervention presented significant improvements in self-perceived QoL, with this significance moving toward anxiety\/depression and responsible alcohol consumption. Those who completed the study indicated a high degree of satisfaction with it and adhered to scheduled appointments. The PEH who adhered to the study obtained a better initial psychosocial evaluation than those who dropped out. Thus, future studies with more participants would clear up doubts about the tendency of the variables that improved in this study. 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