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The objective of this pilot is to examine the results of the first year of the extensive Orientation on Being (OB) program in the Netherlands. A prospective and quasi-experimental design was used in which changes in various indices of psychological functioning of OB participants (N = 27) were compared with those of matched participants of the standard 8-week Mindfulness-Based Stress Reduction program (MBSR; N = 54) across a 12-month period. Analyses showed that the OB program was associated with significant changes across the 12\u00a0months in all but one of the studied outcomes: increased psychological well-being, self-esteem, self-compassion, introspective insight, and mindfulness skills, and decreased depressive symptoms, anxiety, perceived stress and rumination (all with large effect sizes). Differences between the two programs were absent at 2\u00a0months, but a significant Time \u00d7 Group interaction reflected that the OB group further strengthened its beneficial changes between 2 and 12\u00a0months, which were not evident in the MBSR group. These results indicate that the OB program was associated with persistent large benefits for psychological functioning. Future studies should employ larger samples in a randomized controlled trial.<\/jats:p>","DOI":"10.1177\/00332941261463476","type":"journal-article","created":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T04:59:12Z","timestamp":1784609952000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["The Orientation on Being Program: A Prospective Pilot Study Comparing Its Results With the Standard Mindfulness-Based Stress Reduction Program"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1023-978X","authenticated-orcid":false,"given":"Cees","family":"Hoefnagels","sequence":"first","affiliation":[{"name":"Department of Research and Innovation, Senior Researcher in Ceesstudies"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Nykl\u00ed\u010dek","sequence":"additional","affiliation":[{"name":"Tilburg University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,20]]},"reference":[{"key":"e_1_3_7_2_1","doi-asserted-by":"publisher","DOI":"10.1089\/acm.2015.0177"},{"issue":"2","key":"e_1_3_7_3_1","first-page":"II27","article-title":"Validity of the five-item WHO well-being index (WHO-5) in an elderly population","volume":"251","author":"Bonsignore M.","year":"2001","unstructured":"Bonsignore M., Barkow K., Jessen F., Heun R. (2001). Validity of the five-item WHO well-being index (WHO-5) in an elderly population. European Archives of Psychiatry and Clinical Neuroscience, 251(Suppl 2), II27\u2013II31. https:\/\/doi.org\/10.1007\/BF03035123","journal-title":"European Archives of Psychiatry and Clinical Neuroscience"},{"key":"e_1_3_7_4_1","doi-asserted-by":"crossref","unstructured":"Britton W. B. Desbordes G. Acabchuk R. Peters S. Lindahl J. R. Canby N. K. Vago D. R. Dumais T. Lipsky J. Kimmel H. Sager L. Rahrig H. Cheaito A. Acero P. Scharf J. Lazar S. W. Schuman-Olivier Z. Ferrer R. Moitra E. (2021). From self-esteem to selflessness: An evidence (gap) map of self-related processes as mechanisms of mindfulness-based interventions. 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