{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:20:13Z","timestamp":1790716813940,"version":"4.1.0"},"reference-count":48,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T00:00:00Z","timestamp":1685059200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000102","name":"Health Resources and Services Administration","doi-asserted-by":"publisher","award":["U90HA31462"],"award-info":[{"award-number":["U90HA31462"]}],"id":[{"id":"10.13039\/100000102","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Public Health Rep"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Highly effective direct-acting antiviral medications have made it feasible to achieve elimination of hepatis C virus (HCV), including for people with HIV and HCV coinfection. The Centers for Disease Control and Prevention offers guidance for a laboratory surveillance\u2013based HCV viral clearance cascade, which allows public health departments to track the outcomes of people with HCV based on the following steps: ever infected, virally tested, initial infection, and cured or cleared. We examined the feasibility of this approach among people with HIV and HCV coinfection in Connecticut.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We matched an HIV surveillance database, which included cases from the enhanced HIV\/AIDS Reporting System as of December 31, 2019, and the HCV surveillance database, the Connecticut Electronic Disease Surveillance System, to define a cohort of coinfected people. We used HCV laboratory results obtained from January 1, 2016, through August 3, 2020, to determine HCV status.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of 1361 people who were ever infected with HCV as of December 31, 2019, 1256 (92.3%) received HCV viral testing, 865 of 1256 people tested (68.9%) were HCV infected, and 336 of 865 infected people (38.8%) were cleared or cured. People who had undetectable HIV viral loads at most recent HIV test (&lt;200 copies\/mL) were more likely than those with detectable HIV viral loads to achieve HCV cure ( P = .02).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>A surveillance-based approach that includes data based on the Centers for Disease Control and Prevention HCV viral clearance cascade is feasible to implement, can help track population-level outcomes longitudinally, and can help identify gaps to inform HCV elimination strategies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00333549231172173","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T06:57:46Z","timestamp":1685084266000},"page":"208-217","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Implementing a Surveillance-Based Approach to Create a Statewide Viral Clearance Cascade for Hepatitis C Among People With HIV and HCV Coinfection in Connecticut"],"prefix":"10.1177","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6765-594X","authenticated-orcid":false,"given":"Maximilian","family":"Wegener","sequence":"first","affiliation":[{"name":"School of Medicine, Yale University, New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"Brooks","sequence":"additional","affiliation":[{"name":"School of Medicine, Yale University, New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne","family":"Speers","sequence":"additional","affiliation":[{"name":"Connecticut Department of Public Health, Hartford, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Nichols","sequence":"additional","affiliation":[{"name":"School of Medicine, Yale University, New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merceditas","family":"Villanueva","sequence":"additional","affiliation":[{"name":"School of Medicine, Yale University, New Haven, CT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,5,26]]},"reference":[{"key":"bibr1-00333549231172173","doi-asserted-by":"publisher","DOI":"10.5811\/westjem.2018.8.37827"},{"key":"bibr2-00333549231172173","doi-asserted-by":"publisher","DOI":"10.1097\/qad.0000000000002156"},{"key":"bibr3-00333549231172173","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw111"},{"key":"bibr4-00333549231172173","unstructured":"World Health Organization. Global health sector strategy on viral hepatitis 2016-2021: towards ending viral hepatitis. May 17, 2016. Accessed September 25, 2020. https:\/\/www.who.int\/publications\/i\/item\/WHO-HIV-2016.06"},{"key":"bibr5-00333549231172173","unstructured":"Centers for Disease Control and Prevention. Estimated HIV incidence and prevalence in the United States, 2015-2019. HIV Surveill Rep Suppl Rep. 2021;26(1):1-81. Accessed October 22, 2021. http:\/\/www.cdc.gov\/hiv\/library\/reports\/hiv-surveillance.html"},{"key":"bibr6-00333549231172173","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268818000766"},{"key":"bibr7-00333549231172173","unstructured":"Centers for Disease Control and Prevention. People coinfected with HIV and viral hepatitis. Updated September 21, 2020. Accessed September 25, 2020. https:\/\/www.cdc.gov\/hepatitis\/populations\/hiv.htm"},{"key":"bibr8-00333549231172173","doi-asserted-by":"publisher","DOI":"10.7326\/M16-2575"},{"key":"bibr9-00333549231172173","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.08.043"},{"key":"bibr10-00333549231172173","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00485-5"},{"key":"bibr11-00333549231172173","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2016.00296"},{"key":"bibr12-00333549231172173","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.8199"},{"key":"bibr13-00333549231172173","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101554"},{"key":"bibr14-00333549231172173","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1002754"},{"key":"bibr15-00333549231172173","unstructured":"Centers for Disease Control and Prevention, Division of Viral Hepatitis. 2025 Strategic plan. 2020. 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