{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:45:29Z","timestamp":1777898729599,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:00:00Z","timestamp":1697500800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["P30AI060354"],"award-info":[{"award-number":["P30AI060354"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Public Health Rep"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:p>The 2022 mpox (formerly monkeypox) outbreak affected predominantly men who have sex with men (MSM), likely through sexual transmission, which resulted in institutions specializing in sexual health being at the frontlines of the mpox outbreak. Fenway Health in Boston serves close to 10\u2009000 MSM annually, which includes more than 2400 MSM who are living with HIV and 3320 MSM with active HIV preexposure prophylaxis (PrEP) prescriptions. We report on the programs implemented and changes to clinical practice at Fenway Health during the mpox outbreak. Fenway Health diagnosed its first case of mpox in June 2022 and treated this patient with tecovirimat. In early July 2022, Fenway Health administered its first dose of the Jynneos vaccine under the Emergency Use Authorization for protection against mpox. As of October 6, 2022, 69 people had tested positive for the mpox virus at Fenway Health. Among the 69 people who tested positive, 43 (62.3%) self-identified as male, with the remaining not reporting a sex or gender identity, and 40 (58.0%) reported their sexual orientation as gay or bisexual. Twenty-five people (36.2%) were treated with tecovirimat. As of October 30, 2022, Fenway Health had administered 6376 doses of the Jynneos vaccine. The programmatic changes involved in rollout and scale-up of vaccination, treatment, and community outreach services at Fenway Health during the 2022 mpox outbreak that we describe here could inform strategies to address subsequent outbreaks.<\/jats:p>","DOI":"10.1177\/00333549231201682","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T04:33:08Z","timestamp":1697517188000},"page":"294-300","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Addressing mpox at a Frontline Community Health Center: Lessons for the Next Outbreak"],"prefix":"10.1177","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4077-3476","authenticated-orcid":false,"given":"Lao-Tzu","family":"Allan-Blitz","sequence":"first","affiliation":[{"name":"Division of Global Health Equity, Department of Medicine, Brigham and Women\u2019s Hospital, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taimur","family":"Khan","sequence":"additional","affiliation":[{"name":"Fenway Health, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kavya","family":"Elangovan","sequence":"additional","affiliation":[{"name":"Fenway Health, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Smith","sequence":"additional","affiliation":[{"name":"Fenway Health, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ami","family":"Multani","sequence":"additional","affiliation":[{"name":"Fenway Health, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth H.","family":"Mayer","sequence":"additional","affiliation":[{"name":"Fenway Health, Boston, MA, USA"},{"name":"Division of Infectious Diseases, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA"},{"name":"Department of Medicine, Harvard Medical School, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,10,17]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"World Health Organization. Second meeting of the International Health Regulations (2005) (IHR) Emergency Committee regarding the multi-country outbreak of monkeypox. July 23 2022. Accessed September 3 2022. https:\/\/www.who.int\/news\/item\/23-07-2022-second-meeting-of-the-international-health-regulations-(2005)-(ihr)-emergency-committee-regarding-the-multi-country-outbreak-of-monkeypox"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofac310"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2207323"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.2807\/1560-7917.ES.2022.27.22.2200421"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)01436-2"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/OLQ.0000000000001705"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7145a4"},{"key":"e_1_3_3_9_2","unstructured":"Massachusetts Department of Public Health. Monkeypox cases and people vaccinated by age sex and race\/ethnicity. October 6 2022. Accessed October 6 2022. https:\/\/www.mass.gov\/doc\/weekly-report-monkeypox-cases-and-people-vaccinated-october-6-2022\/download"},{"key":"e_1_3_3_10_2","unstructured":"US Food and Drug Administration. Review memorandum: Jynneos (smallpox and monkeypox vaccine live non-replicating). August 9 2022. Accessed September 11 2022. https:\/\/www.fda.gov\/media\/160785\/download"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7122e1"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2019.06.005"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-022-01742-y"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.2105\/ajph.91.6.892"},{"key":"e_1_3_3_15_2","unstructured":"Centers for Disease Control and Prevention. Mpox. Clinical guidance. 2023. Updated January 6 2023. Accessed August 8 2023. https:\/\/www.cdc.gov\/poxvirus\/mpox\/clinicians\/clinical-guidance.html"},{"key":"e_1_3_3_16_2","unstructured":"Massachusetts Department of Public Health. Mpox vaccination. 2023. Updated May 24 2023. Accessed May 10 2023. https:\/\/www.mass.gov\/info-details\/monkeypox-vaccination#eligibility"},{"key":"e_1_3_3_17_2","unstructured":"Centers for Disease Control and Prevention. Mpox: isolation and infection control at home. 2022. Updated August 11 2022. Accessed August 12 2022. https:\/\/www.cdc.gov\/poxvirus\/mpox\/clinicians\/infection-control-home.html"},{"key":"e_1_3_3_18_2","unstructured":"Centers for Disease Control and Prevention. Expanded access IND protocol: use of tecovirimat (TPOXX\u00ae) for treatment of human non-variola orthopoxvirus infections in adults and children. IND no. 116 039. Version 6.3. May 5 2023. Accessed July 17 2023. https:\/\/www.cdc.gov\/poxvirus\/mpox\/pdf\/tecovirimat-ind-protocol-cdc-irb.pdf"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7135e1"},{"key":"e_1_3_3_20_2","unstructured":"Fenway Health. Mpox information. 2023. Updated May 24 2023. Accessed August 8 2023. https:\/\/fenwayhealth.org\/care\/medical\/mpox"},{"key":"e_1_3_3_21_2","unstructured":"Fenway Health. Fenway Health provides blueprint for more effective federal response to monkeypox. September 12 2022. Accessed November 9 2022. https:\/\/fenwayhealth.org\/fenway-health-provides-blueprint-for-more-effective-federal-response-to-monkeypox"},{"key":"e_1_3_3_22_2","unstructured":"World Health Organization. 2022 Monkeypox outbreak: global trends. 2022. Updated November 9 2022. Accessed November 9 2022. https:\/\/worldhealthorg.shinyapps.io\/mpx_global\/#1_Overview"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7149a5"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7132e3"},{"key":"e_1_3_3_25_2","unstructured":"Howard Brown Health. Howard Brown Health identifies monkeypox (mpox) resurgence. Press release. May 5 2023. Accessed May 8 2023. https:\/\/howardbrown.org\/press\/howard-brown-health-identifies-monkeypox-mpox-resurgence"}],"container-title":["Public Health Reports\u00ae"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00333549231201682","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00333549231201682","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00333549231201682","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T09:39:17Z","timestamp":1777628357000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00333549231201682"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,17]]},"references-count":24,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,5]]}},"alternative-id":["10.1177\/00333549231201682"],"URL":"https:\/\/doi.org\/10.1177\/00333549231201682","relation":{},"ISSN":["0033-3549","1468-2877"],"issn-type":[{"value":"0033-3549","type":"print"},{"value":"1468-2877","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,17]]}}}