{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T02:50:20Z","timestamp":1777863020204,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[1931,6,1]],"date-time":"1931-06-01T00:00:00Z","timestamp":-1217721600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Proceedings of the Royal Society of Medicine"],"published-print":{"date-parts":[[1931,6]]},"abstract":"<jats:p>The difference between h\u00e6mopathies (which originate in the blood-forming tissues) and blood-diseases (which develop in the blood-stream) is explained and illustrated by examples and specimens.<\/jats:p>\n                  <jats:p>Primary an\u00e6mia caused by the hyperplasia of the erythroblastic tissues in the marrow occurs in fowls as erythromyelosis. This condition can be experimentally transmitted, though inoculation in fowls may reproduce the an\u00e6mic disease, or give rise to a persistent polyerythrocyth\u00e6mia. On farms erythromyelosis is often, but not always, associated with the cestode, Davainea proglottina.<\/jats:p>\n                  <jats:p>Secondary an\u00e6mia develops in splenectomized rats following the invasion of the erythrocytes by Bartonella muris. The subsequent erythrocytolysis may induce h\u00e6moglobinuria, similar to that occurring in man and cattle as the result of certain h\u00e6mic infections.<\/jats:p>\n                  <jats:p>Oligoerythrocyth\u00e6mia is frequently seen in fowls associated with leucocyth\u00e6mia; the deficiency of the red blood-corpuscles is due to the pressure on the erythroblastic sinusoids, by the proliferation of the myeloblastic or lymphoblastic tissues in the marrow.<\/jats:p>\n                  <jats:p>Lymphocyth\u00e6mia (and lymphomatosis) have been observed in canaries, fowls, mice and guinea-pigs. The conditions can be experimentally transmitted within the species; inoculation with lymphocyth\u00e6mic blood may reproduce the h\u00e6mic type or induce the development of scattered tumour-like deposits (lymphomatosis). Whichever type of lesion results, the pathological cell unit is one of the lymphoblast-lymphocyte series.<\/jats:p>\n                  <jats:p>Fowl leucocyth\u00e6mia originates through the morbid proliferation and premature entry into the circulation of cells of the myeloblast-granulocyte series. On inoculation in fowls the original leucocyth\u00e6mia may be reproduced; rarely there follows the development of localized deposits of myeloblastic cells in the skin.<\/jats:p>\n                  <jats:p>As these diseases of the blood-forming system, and those occurring in man and cattle offer many striking resemblances, it may be suggested that the determination of the origin of the particular type of cell encountered should serve as guide to diagnosis and classification in all h\u00e6mopathies.<\/jats:p>","DOI":"10.1177\/003591573102400889","type":"journal-article","created":{"date-parts":[[2019,7,19]],"date-time":"2019-07-19T03:24:11Z","timestamp":1563506651000},"page":"1141-1156","source":"Crossref","is-referenced-by-count":1,"title":["Discussion on the Pathology and Treatment of H\u00e6mopathies, Including Leuk\u00e6mias, of Man and Animals"],"prefix":"10.1177","volume":"24","author":[{"given":"H. P.","family":"Bayon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2016,9]]},"reference":[{"key":"bibr-bibr2-003591573102400889","first-page":"1","author":"Askanazy M.","year":"1930","journal-title":"Le Sang"},{"issue":"3","key":"bibr-bibr3-003591573102400889","first-page":"163","author":"Battaglia F.","year":"1929","journal-title":"Arch. Sc. Med."},{"key":"bibr-bibr4-003591573102400889","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/S0368-1742(30)80021-3","author":"Bayon H. P.","year":"1930","journal-title":"Journ. Comp. Path."},{"key":"bibr-bibr5-003591573102400889","first-page":"309","author":"Brumpt E.","year":"1930","journal-title":"Ann. de Paras."},{"key":"bibr-bibr6-003591573102400889","first-page":"405","author":"Emile-Weil P.","year":"1930","journal-title":"Le Sang"},{"key":"bibr-bibr7-003591573102400889","first-page":"649","author":"Emile-Weil P.","year":"1930","journal-title":"Le Sang"},{"key":"bibr-bibr8-003591573102400889","first-page":"165","author":"Haaland M.","year":"1905","journal-title":"Ann. Inst. Past."},{"key":"bibr-bibr9-003591573102400889","first-page":"391","author":"Honda Y.","year":"1930","journal-title":"Jap. J. Exper. Med."},{"key":"bibr-bibr10-003591573102400889","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/BF01634507","author":"Korteweg R.","year":"1929","journal-title":"Zt. f. Krebsf."},{"key":"bibr-bibr13-003591573102400889","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1084\/jem.51.4.659","author":"Richter M. E.","year":"1930","journal-title":"Journ. Exper. Med."},{"key":"bibr-bibr14-003591573102400889","first-page":"1256","author":"Snuders E. P.","year":"1926","journal-title":"Ned. Tijd. Genesk."},{"key":"bibr-bibr15-003591573102400889","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1007\/BF01733740","author":"Weber F. P.","year":"1930","journal-title":"Klin. Wochens."}],"container-title":["Proceedings of the Royal Society of Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/003591573102400889","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/003591573102400889","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:19:26Z","timestamp":1777526366000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.sagepub.com\/doi\/10.1177\/003591573102400889"}},"subtitle":["The H\u00e6mopathies of Laboratory Animals"],"short-title":[],"issued":{"date-parts":[[1931,6]]},"references-count":12,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2016,9]]},"published-print":{"date-parts":[[1931,6]]}},"alternative-id":["10.1177\/003591573102400889"],"URL":"https:\/\/doi.org\/10.1177\/003591573102400889","relation":{},"ISSN":["0035-9157"],"issn-type":[{"value":"0035-9157","type":"print"}],"subject":[],"published":{"date-parts":[[1931,6]]}}}