{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T14:41:18Z","timestamp":1780584078673,"version":"3.54.1"},"reference-count":19,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"The relevance and clinical significance between NO concentration of nose expiratory and allergic rhinitis","award":["19SYPYB-14"],"award-info":[{"award-number":["19SYPYB-14"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>Benign paroxysmal positional vertigo is characterized by recurrence, which exposes patients to repeated vertigo attacks. Vitamin D deficiency has been found to be a risk factor in benign paroxysmal positional vertigo, although effect of its elimination on recurrence reduction remains unknown. To determine the effect of vitamin D supplementation in preventing recurrence of benign paroxysmal positional vertigo patients with vitamin D deficiency using a meta-analysis study. We searched and retrieved relevant articles from several databases, then used the Cochrane evaluation system or Methodological Index for Non-Randomized Studies (MINORS) to assess the quality of studies. We adopted risk-ratio (RR) with corresponding 95% confidence interval (CI) to determine effect sizes, and further performed statistical analyses under a randomized- or fixed-effects model. Seven studies, comprising 602 and 731 participants in the case and control group respectively, met our inclusion criteria, and were therefore included in the meta-analysis. Assessment based on Cochrane evaluation system or MINORS revealed that most of the studies had high quality. Moreover, the randomized- model revealed that the vitamin D supplementation group had a lower recurrence rate than the control group which did not accepted vitamin D supplementation (RR\u2009=\u20090.41, 95% CI\u2009=\u20090.26\u20130.65, p\u2009&lt;\u20090.01). Overall, these findings indicate that vitamin D supplementation can significantly lower recurrence in benign paroxysmal positional vertigo and vitamin D deficiency.<\/jats:p>","DOI":"10.1177\/00368504211024569","type":"journal-article","created":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T12:29:22Z","timestamp":1623760162000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Effect of vitamin D supplementation on benign paroxysmal positional vertigo recurrence: A meta-analysis"],"prefix":"10.1177","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1970-6113","authenticated-orcid":false,"given":"Zhiling","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Gansu Provincial People\u2019s Hospital, Lanzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juanli","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Gansu Provincial People\u2019s Hospital, Lanzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenzhen","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Gansu Provincial People\u2019s Hospital, Lanzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"He","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Gansu Provincial People\u2019s Hospital, Lanzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xudong","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Gansu Provincial People\u2019s Hospital, Lanzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, The First Hospital of Lanzhou University, Lanzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,6,15]]},"reference":[{"key":"bibr1-00368504211024569","first-page":"67","volume":"82","author":"Instrum RS","year":"2019","journal-title":"Adv Otorhinolaryngol"},{"key":"bibr2-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(00)70190-2"},{"key":"bibr3-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000175987.59991.3d"},{"key":"bibr4-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2006.02.083"},{"key":"bibr5-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24099"},{"key":"bibr6-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-018-5146-6"},{"key":"bibr7-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(00)70187-2"},{"key":"bibr8-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-004-0841-x"},{"key":"bibr9-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2012.11.029"},{"issue":"3","key":"bibr10-00368504211024569","first-page":"173","volume":"7","author":"Sheikhzadeh M","journal-title":"Caspian J Intern Med"},{"key":"bibr11-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2015.08.009"},{"key":"bibr12-00368504211024569","unstructured":"Califano L, Salafia F, Melillo MG, et al. Is hypovitaminosis D a risk factor for either the onset or the recurrence of Benign Paroxysmal Positional Vertigo.\n                      Frontiera ORL\n                      2014; 144 Pt A:138\u2013145."},{"key":"bibr13-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1080\/21695717.2019.1590988"},{"key":"bibr14-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-3402431"},{"key":"bibr15-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000010343"},{"key":"bibr16-00368504211024569","doi-asserted-by":"publisher","DOI":"10.17116\/otorino20198406128"},{"key":"bibr17-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2013.11.003"},{"key":"bibr18-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000002258"},{"key":"bibr19-00368504211024569","doi-asserted-by":"publisher","DOI":"10.1016\/j.pedneo.2019.04.007"}],"container-title":["Science Progress"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00368504211024569","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00368504211024569","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00368504211024569","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:04:32Z","timestamp":1777633472000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00368504211024569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1177\/00368504211024569"],"URL":"https:\/\/doi.org\/10.1177\/00368504211024569","relation":{},"ISSN":["0036-8504","2047-7163"],"issn-type":[{"value":"0036-8504","type":"print"},{"value":"2047-7163","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4]]},"article-number":"00368504211024569"}}