{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:34:09Z","timestamp":1777901649714,"version":"3.51.4"},"reference-count":54,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"the Key Laboratory of Nephrology, Guangdong Province","award":["2020B1212060028"],"award-info":[{"award-number":["2020B1212060028"]}]},{"name":"Science and Technology Program of Guangzhou, China","award":["201804020049"],"award-info":[{"award-number":["201804020049"]}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2020A1515010241"],"award-info":[{"award-number":["2020A1515010241"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Key Laboratory of National Health Commission","award":["2002B60118"],"award-info":[{"award-number":["2002B60118"]}]},{"name":"the Chinese National Key Technology R and D Program, Ministry of Science and Technology","award":["No.2016YFC0906101"],"award-info":[{"award-number":["No.2016YFC0906101"]}]},{"name":"the Chinese National Key Technology R and D Program, Ministry of Science and Technology","award":["No.2016YFC0906100"],"award-info":[{"award-number":["No.2016YFC0906100"]}]},{"name":"the Chinese National Key Technology R and D Program, Ministry of Science and Technology","award":["No.2017YFC0907601"],"award-info":[{"award-number":["No.2017YFC0907601"]}]},{"name":"the Chinese National Key Technology R and D Program, Ministry of Science and Technology","award":["No.2017YFC0907602"],"award-info":[{"award-number":["No.2017YFC0907602"]}]},{"name":"the Chinese National Key Technology R and D Program, Ministry of Science and Technology","award":["No.2017YFC0907603"],"award-info":[{"award-number":["No.2017YFC0907603"]}]},{"DOI":"10.13039\/501100021171","name":"Guangdong Basic and Applied Basic Research Foundation","doi-asserted-by":"crossref","award":["2019A1515010992"],"award-info":[{"award-number":["2019A1515010992"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Systemic lupus erythematosus is a common autoimmune disease involving multiple systems. Clinical involvement of the central and peripheral nervous systems is not unusual, but peripheral neuropathy in systemic lupus erythematosus with chronic inflammatory demyelinating polyneuropathy is uncommon. Our study aimed to illustrate the clinical features, diagnosis, and treatment of systemic lupus erythematosus combined with chronic inflammatory demyelinating polyneuropathy, and to aid in the identification of peripheral neuropathy in systemic lupus erythematosus.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This article reports a case of systemic lupus erythematosus with onset in pregnancy, with chronic inflammatory demyelinating polyneuropathy as the first manifestation. We then analyze the identification of common peripheral neuropathy in systemic lupus erythematosus in detail, based on a literature review of confirmed cases of systemic lupus erythematosus combined with chronic inflammatory demyelinating polyneuropathy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A 34-year-old woman presented progressive muscle weakness and muscular atrophy in the extremities during pregnancy, 3 years previously. At 4 months after onset, she had completely lost the ability to hold objects and walk, and had slight numbness in the limbs, without paresthesia. Her condition was misdiagnosed as \u201cmotor neuron disease\u201d at the time. Three years after onset, her condition was revisited because of nephrotic syndrome, and she was diagnosed with nephrotic syndrome and peripheral nerve injury caused by systemic lupus erythematosus. After immunosuppressive treatment with corticosteroids and intravenous cyclophosphamide, her symptoms of muscle weakness were markedly improved. This article summarizes the characteristics of systemic lupus erythematosus combined with chronic inflammatory demyelinating polyneuropathy that have been reported in the literature, from the aspects of morbidity, disease progression, nerve injury, laboratory examinations, and treatment response.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Our identification of a common peripheral neuropathy in systemic lupus erythematosus will help to improve clinicians\u2019 understanding of various peripheral neuropathies in systemic lupus erythematosus. It will also aid in the early diagnosis and treatment of such patients, thus improving their long-term prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00368504211050276","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T13:54:47Z","timestamp":1640267687000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Progressive muscle weakness and amyotrophy during pregnancy as the first manifestation of systemic lupus erythematosus: A case report and review of literature"],"prefix":"10.1177","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4812-0506","authenticated-orcid":false,"given":"Liu","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, China"},{"name":"Key Laboratory of Nephrology, Ministry of Health and Guangdong Province, 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