{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T03:25:40Z","timestamp":1778901940050,"version":"3.51.4"},"reference-count":42,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"a Dongnam Institute of Radiological and Medical Sciences (DIRAMS) grant funded by the Korean government","award":["50491-2023"],"award-info":[{"award-number":["50491-2023"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:p>The purpose of this study was to establish the dose\u2013response curves for biological dosimetry of the Dong Nam Institute of Radiological and Medical Sciences to monitor radiation exposure of local residents in the vicinity of the nuclear power plant. The blood samples of five healthy volunteers were irradiated with gamma ray, and each sample was divided equally for analysis of chromosomal aberrations by Giemsa staining and three-color fluorescence in situ hybridization painting of the triplet (chromosomes #1, #2, and #4). The results of chromosomal aberrations followed the Poisson distribution in all individual and averaged data which include inter-individual variation in radiation susceptibility. Cytogenetics Dose Estimate Software version 5.2 was used to fit the dose\u2013response curve and to determine the coefficients of linear\u2013quadratic equations. The goodness of fit of the curves and statistical significance of fitted \u03b1 and \u03b2-coefficients were confirmed in both Giemsa-based dicentric analysis and FISH-based translocation analysis. The coefficients calculated from the five-donor average data were almost identical in both of the analyses. We also present the results that the dose-response curve for dicentric chromosomes plus fragments could be more effective for dose estimation following low-dose radiation accidents.<\/jats:p>","DOI":"10.1177\/00368504231198935","type":"journal-article","created":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T17:05:16Z","timestamp":1695920716000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Biological dosimetry dose-response curves for residents living near nuclear power plants in South Korea"],"prefix":"10.1177","volume":"106","author":[{"given":"Soo Kyung","family":"Jeong","sequence":"first","affiliation":[{"name":"Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Gijang-gun, Busan, Republic of Korea"},{"name":"Department of Microbiology, Dong-A University College of Medicine, Seo-gu, Busan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su Jung","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Gijang-gun, Busan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yeong-Rok","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Gijang-gun, Busan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HyoJin","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Research Center, Dongnam Institute of Radiological & Medical Sciences, Gijang-gun, Busan, Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Uk","family":"Kye","sequence":"additional","affiliation":[{"name":"Department of Research Center, Dongnam Institute of Radiological & Medical 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