{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T16:19:23Z","timestamp":1779898763467,"version":"3.53.1"},"reference-count":20,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008238","name":"Hebei Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["22377762D"],"award-info":[{"award-number":["22377762D"]}],"id":[{"id":"10.13039\/501100008238","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008240","name":"Department of Health of Hebei Province","doi-asserted-by":"publisher","award":["20220975"],"award-info":[{"award-number":["20220975"]}],"id":[{"id":"10.13039\/501100008240","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008240","name":"Department of Health of Hebei Province","doi-asserted-by":"publisher","award":["20221200"],"award-info":[{"award-number":["20221200"]}],"id":[{"id":"10.13039\/501100008240","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The purpose of this study was to investigate the fluctuations in the prevalence of individuals diagnosed with otitis media with effusion (OME) during the SARS-CoV-2 pandemic, while also evaluating the persistence of SARS-CoV-2 in middle ear effusion (MEE) and assessing the effectiveness of tympanocentesis as a treatment modality for OME in this specific period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The total number of outpatients and patients diagnosed with OME in our department was recorded for January 2022 and January 2023. Thirty patients (aged 15\u201386 years) were categorized into two groups: group A (n\u2009=\u200912), who developed OME during their SARS-CoV-2 infection and group B (n\u2009=\u200918), who experienced OME after the resolution of SARS-CoV-2 infection. All patients underwent otoendoscopic tympanocentesis (without a ventilation tube), where MEE and nasopharyngeal secretions were simultaneously collected for SARS-CoV-2 detection by polymerase chain reaction. The time interval from SARS-CoV-2 infection to tympanocentesis, results of SARS-CoV-2 detection, preoperative and postoperative average hearing threshold, and Eustachian Tube Dysfunction Questionnaire (ETDQ-7) scores were documented.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The proportion of outpatients with OME in January 2023 was higher than that in January 2022. There were five patients who had positive test results for SARS-CoV-2 on MEE after tympanocentesis. These 5 patients underwent tympanocentesis at a mean of 28\u2009\u00b1\u20097.28 days following confirmation of SARS-CoV-2 infection. The ETDQ-7 scores of group A exhibited a reduction from 21.85\u2009\u00b1\u20094.8 to 10.00\u2009\u00b1\u20094.07 following tympanocentesis, while the ETDQ-7 scores of group B also demonstrated a decrease from 21.22\u2009\u00b1\u20094.65 to 10.11\u2009\u00b1\u20093.68 after undergoing tympanocentesis. The tympanocentesis was effective in both groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The study confirmed that the proportion of outpatients with OME in the Clinics of Otolaryngology during the SARS-CoV-2 epidemic increased significantly. SARS-CoV-2 RNA was detectable in MEE of COVID-19-related OME patients. Tympanocentesis was therapeutic for OME during SARS-CoV-2 infection, which facilitated viral clearance in MEE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00368504241231659","type":"journal-article","created":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T02:07:24Z","timestamp":1707962844000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Otitis media with effusion in adults during the SARS-CoV-2 epidemic"],"prefix":"10.1177","volume":"107","author":[{"given":"Yu","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feifei","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"He","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinan","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yushuang","family":"Bai","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingrui","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3063-7080","authenticated-orcid":false,"given":"Zhanchi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Human Anatomy, Hebei Medical University, Shijiazhuang, China"},{"name":"Hebei Key Laboratory of Neurodegenerative Disease Mechanism, Hebei Medical University, Shijiazhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1218-8461","authenticated-orcid":false,"given":"Feng","family":"Luan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The Third Hospital of Hebei Medical University, Shijiazhuang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,14]]},"reference":[{"key":"bibr1-00368504241231659","unstructured":"World Health Organization. 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