{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T15:59:47Z","timestamp":1783353587714,"version":"3.54.6"},"reference-count":10,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>Infectious mononucleosis (IM) is a benign lymphoproliferative disorder primarily caused by the Epstein\u2013Barr virus (human gamma-herpesvirus 4) and most commonly affects 15\u201324-year-old individuals. Spontaneous splenic ruptures occur in 0.1% to 0.5% of patients with IM and can be life-threatening despite reports of suppurative processes involving the tonsils, such as intra-amygdala or peritonsillar abscesses. However, these rare complications can easily be misdiagnosed as acute suppurative tonsillitis caused by typical bacterial infection. This paper reports a case of a teenager with IM and concurrent suppurative tonsillitis, who was initially misdiagnosed with acute bacterial tonsillitis and failed to respond to antibiotic treatment. Examination confirmed IM combined with suppurative tonsillitis. Notably, his symptoms improved significantly after antiviral treatment. Therefore, we suggest that IM-complicating suppurative tonsillitis should be excluded when acute suppurative tonsillitis does not respond to antibiotic treatment and antiviral treatment strategies are urgently needed to avoid serious life-threatening complications.<\/jats:p>","DOI":"10.1177\/00368504251344169","type":"journal-article","created":{"date-parts":[[2025,5,23]],"date-time":"2025-05-23T04:04:36Z","timestamp":1747973076000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["A case of suppurative tonsillitis as a complication of acute infectious mononucleosis"],"prefix":"10.1177","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7679-4837","authenticated-orcid":false,"given":"Changqing","family":"Wang","sequence":"first","affiliation":[{"name":"People's Hospital of Xishuangbanna Dai Nationality Autonomous Prefecture"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifu","family":"Duan","sequence":"additional","affiliation":[{"name":"Zigong First People's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peilin","family":"Li","sequence":"additional","affiliation":[{"name":"People's Hospital of Xishuangbanna Dai Nationality Autonomous Prefecture"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenmin","family":"Zhao","sequence":"additional","affiliation":[{"name":"People's Hospital of Xishuangbanna Dai Nationality Autonomous Prefecture"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianbao","family":"Cao","sequence":"additional","affiliation":[{"name":"The First People's Hospital of Yunnan Province"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,23]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1327856"},{"key":"e_1_3_3_3_2","first-page":"35","article-title":"Tonsillitis and tonsilloliths: diagnosis and management","volume":"107","author":"Smith KL","year":"2023","unstructured":"Smith KL, Hughes R, Myrex P. Tonsillitis and tonsilloliths: diagnosis and management. Am Fam Physician 2023; 107: 35\u201341.","journal-title":"Am Fam Physician"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.idcr.2023.e01829"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.2174\/1573396320666230801091558"},{"key":"e_1_3_3_7_2","unstructured":"Mohseni M Boniface MP Graham C. Mononucleosis. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK470387\/."},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.5114\/ceh.2023.133169"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/535738"},{"key":"e_1_3_3_10_2","article-title":"Low rate of co-infection in complicated infectious mononucleosis","volume":"66","author":"Danstrup CS","year":"2019","unstructured":"Danstrup CS, Klug TE. Low rate of co-infection in complicated infectious mononucleosis. Dan Med J 2019; 66: A5564.","journal-title":"Dan Med J"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/ijd.14887"}],"container-title":["Science Progress"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00368504251344169","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00368504251344169","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00368504251344169","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:16:05Z","timestamp":1777634165000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00368504251344169"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1177\/00368504251344169"],"URL":"https:\/\/doi.org\/10.1177\/00368504251344169","relation":{},"ISSN":["0036-8504","2047-7163"],"issn-type":[{"value":"0036-8504","type":"print"},{"value":"2047-7163","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"article-number":"00368504251344169"}}