{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T01:20:27Z","timestamp":1787275227965,"version":"build-2736575974"},"reference-count":11,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>Chronic limb-threatening ischemia represents the most severe form of peripheral arterial disease, with a 40% amputation rate and 20% mortality at 6 months without revascularization. Deep venous arterialization is an alternative for patients with advanced peripheral arterial disease who have no conventional revascularization surgery option based on their anatomy\u2014no distal artery target to redirect arterial blood. Hybrid deep venous arterialization, which combines open surgical bypass with venous endovascular arterialization and valvulotomy, is a technique under investigation for limb salvage with limited current long-term data. We present a successful limb salvage case report of an early 60s male with no conventional revascularization options who presented with a wound in his foot and underwent a successful hybrid deep venous arterialization. The hybrid deep venous arterialization technique has shown promising preliminary results for long-term limb salvage at 5 years after surgery. This case report establishes a tangible example of the potential role of hybrid deep venous arterialization in the management of patients with no-option chronic limb-threatening ischemia. After a 5-year follow-up, the reported patient has no ischemic symptoms, and he is able to ambulate without support.<\/jats:p>","DOI":"10.1177\/00368504251352033","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T02:57:46Z","timestamp":1750906666000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A 5-year limb salvage for long-term limb salvage in chronic limb-threatening ischemia without options for revascularization, utilizing a hybrid deep venous arterialization technique: A case report"],"prefix":"10.1177","volume":"108","author":[{"given":"Lucas","family":"Ferrer","sequence":"first","affiliation":[{"name":"University of Texas at Austin Dell Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynsey","family":"Malin","sequence":"additional","affiliation":[{"name":"University of Texas at Austin Dell Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8352-5667","authenticated-orcid":false,"given":"Panagiotis","family":"Koutakis","sequence":"additional","affiliation":[{"name":"University of West Florida"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2407-4552","authenticated-orcid":false,"given":"Dimitrios","family":"Miserlis","sequence":"additional","affiliation":[{"name":"University of Texas at Austin Dell Medical School"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,6,25]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.303504"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2014.07.002"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00525.2012"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2015.07.065"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.23736\/S0021-9509.18.10572-6"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2018.11.008"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2019.10.085"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1393976"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/head.12246"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/1526602818820792"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2212754"}],"container-title":["Science Progress"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00368504251352033","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00368504251352033","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00368504251352033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:16:31Z","timestamp":1777634191000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00368504251352033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,4]]}},"alternative-id":["10.1177\/00368504251352033"],"URL":"https:\/\/doi.org\/10.1177\/00368504251352033","relation":{},"ISSN":["0036-8504","2047-7163"],"issn-type":[{"value":"0036-8504","type":"print"},{"value":"2047-7163","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4]]},"article-number":"00368504251352033"}}