{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T13:16:50Z","timestamp":1788787010568,"version":"build-2803163510"},"reference-count":32,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Cardiac syndrome Y (CSY) phenomenon is characterized by the gradual opacification of the coronary vasculature at the distal level. The leuko-glycemic index (LGI) is a blood glucose and white blood cell count index. This study investigates the relationship between CSY and the leuko-glycemic index.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A case-control, retrospective study was conducted. Consecutively selected individuals with complaints of angina were included in the study. Subjects with normal coronary flow (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u2009132) and coronary slow flow (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      \u2009=\u2009136) were classified, after confirmation of coronary angiography results.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The age ranges were recorded as 57 (48\u201364) for the NCF group vs. 52 (46\u201358) for the CSY group,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009=\u2009.010. The mean hematocrit (Hct), Hemoglobin (Hg), White blood cells (WBC), and LGI were significantly higher in the CSY group than in the normal coronary flow group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001). Accordingly, CSY was positively correlated with Hct, Hg, and WBC (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u2009.001). ROC curve analysis indicated that a cut-off value of \u22659.28 for the LGI predicted CSF with a sensitivity of 78% and a specificity of 78.1% [Area under the curve (AUC): 0.626 and 95% CI: 0.559\u20130.693].\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this study, we show for the first time that elevated LGI levels can independently predict CSF formation in the subclinical process.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00368504251356562","type":"journal-article","created":{"date-parts":[[2025,7,21]],"date-time":"2025-07-21T04:59:47Z","timestamp":1753073987000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Prognostic capacity of the leuko-glycemic index in cardiac syndrome Y"],"prefix":"10.1177","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7234-6321","authenticated-orcid":false,"given":"Muhammed Bahad\u0131r","family":"Omar","sequence":"first","affiliation":[{"name":"Umraniye Training and Research Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8459-3418","authenticated-orcid":false,"given":"Emre","family":"Eynel","sequence":"additional","affiliation":[{"name":"Umraniye Training and Research Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-8938-6395","authenticated-orcid":false,"given":"Sena","family":"Nasif","sequence":"additional","affiliation":[{"name":"Umraniye Training and Research Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8923-8709","authenticated-orcid":false,"given":"Kenan","family":"Toprak","sequence":"additional","affiliation":[{"name":"Harran Universitesi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9008-6631","authenticated-orcid":false,"given":"Mustafa Be\u011fen\u00e7","family":"Ta\u015fcanov","sequence":"additional","affiliation":[{"name":"Harran Universitesi"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,7,20]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(72)90307-9"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.15420\/ecr.2021.46"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1177\/00033197211004390"},{"key":"e_1_3_2_5_2","first-page":"462","article-title":"Clinical manifestations of slow coronary flow from acute coronary syndrome to serious arrhythmias","volume":"16","author":"Wozakowska-Kap\u0142on B","year":"2009","unstructured":"Wozakowska-Kap\u0142on B, Niedziela J, Krzyzak P, et al. 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Prognostic value of the leuko-glycemic Index in acute myocardial infarction; a systematic review and meta-analysis. Arch Acad Emerg Med 2023 Mar 1; 11: e25.","journal-title":"Arch Acad Emerg Med"},{"key":"e_1_3_2_12_2","first-page":"142","article-title":"\u00cdndice leucogluc\u00e9mico en pacientes con infarto mioc\u00e1rdico con elevaci\u00f3n del ST [leuko-glycemic index in patients with ST elevation myocardial infarction]","volume":"60","author":"Reyes-Villarreal JC","year":"2022","unstructured":"Reyes-Villarreal JC, Morales-Guti\u00e9rrez JE, L\u00f3pez-Zamora B, et al. \u00cdndice leucogluc\u00e9mico en pacientes con infarto mioc\u00e1rdico con elevaci\u00f3n del ST [leuko-glycemic index in patients with ST elevation myocardial infarction]. 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