{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T09:58:55Z","timestamp":1783763935154,"version":"3.55.0"},"reference-count":34,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the Natural Science Foundation of Guangdong Province","award":["2024A1515012935"],"award-info":[{"award-number":["2024A1515012935"]}]},{"name":"the Demonstration Project of Technological Innovation of Hubei Province","award":["2022BCE031"],"award-info":[{"award-number":["2022BCE031"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Previous studies suggest that obesity may exacerbate clinical manifestations of chronic obstructive pulmonary disease (COPD). Early detection of COPD could improve therapeutic outcomes. This study investigates the relationship between a novel metabolic biomarker, the Visceral Adiposity Index (VAI), and COPD risk. We hypothesized that higher VAI levels would be independently associated with an increased prevalence of COPD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study is a cross-sectional analysis of data from the National Health and Nutrition Examination Survey (NHANES) spanning the periods 1999\u20132018 and 2021\u20132023. Multivariable logistic regression was employed to assess the association between VAI and COPD, supplemented by subgroup stratification, smoothed curve fitting, and threshold effect analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 16,167 participants, 1397 were diagnosed with COPD. Multivariable logistic regression revealed a positive correlation between VAI levels and COPD prevalence, independent of confounding factors. Subgroup analyses indicated stronger associations in hypertensive patients and females. Smoothed curve fitting identified a threshold effect for VAI, with an inflection point at 2.55 (P\u2009=\u20090.002).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings of this study indicate a significant positive correlation between VAI levels and the prevalence of COPD. Maybe incorporating visceral adipose function assessment into the initial risk stratification system for high-risk populations with COPD holds certain clinical value.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00368504251406570","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T16:45:59Z","timestamp":1765471559000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Association between visceral adiposity index and chronic obstructive pulmonary disease: A cross-sectional analysis"],"prefix":"10.1177","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1981-8588","authenticated-orcid":false,"given":"Shaofeng","family":"Zhang","sequence":"first","affiliation":[{"name":"China Three Gorges University, Yichang Central People's Hospital"},{"name":"Department of Respiratory and Critical Care Medicine, Yichang Central People's Hospital, Yichang, Hubei, China"},{"name":"Hubei Provincial Clinical Medical Research Center for Precision Diagnosis and Treatment of Lung Cancer and Management of Advanced Cancer Pain, Yichang, Hubei, China"},{"name":"Pulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, Guangdong, China"},{"name":"Pulmonary and Critical Care Medicine, The Eighth Affiliated Hospital of Southern Medical University (The First People's Hospital of Shunde, Foshan), Foshan, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yidan","family":"Lin","sequence":"additional","affiliation":[{"name":"Southern Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zekui","family":"Fang","sequence":"additional","affiliation":[{"name":"Pulmonary and Critical Care Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, Guangdong, 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