{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:03:28Z","timestamp":1787018608669,"version":"build-2736575974"},"reference-count":24,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To evaluate whether nasal septum deviation type is associated with intraoperative mucoperichondrial perforation during septoplasty.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this prospective observational cohort at Ba\u011fc\u0131lar Training and Research Hospital (Istanbul, T\u00fcrkiye), 133 adults undergoing septoplasty for nasal obstruction were classified by the Mladina system. The primary outcome was the occurrence of mucoperichondrial perforation during surgery; secondary outcomes were laterality and the largest tear dimension. Group differences across deviation types were analyzed with appropriate comparative statistics; two-sided\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u20090.05 was considered significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Perforation occurred in 63 of 133 patients (47.4%). Most tears were unilateral (98.4%); one patient (0.8%) had bilateral tears constituting a septal perforation. Perforation incidence differed by deviation type (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u20090.001): Type I, 5.9%; Type II, 31.3%; Type III, 37.8%; Type IV, 78.6%; Type V, 65.2%; Type VI, 60.0%; and Type VII, 83.3%. Mean tear size increased with deviation complexity, measuring \u223c2\u20135\u2005mm in Types I\u2013III versus 6\u20138\u2005mm in Types IV\u2013VII (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2009&lt;\u20090.05). Perforation frequency and size did not differ between surgeons.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Nasal septum deviation morphology is strongly associated with the risk and extent of mucoperichondrial perforation during septoplasty. Patients with complex deviation patterns (Types IV\u2013VII) have a substantially higher risk; recognizing these patterns preoperatively may inform counseling and encourage meticulous dissection strategies to reduce mucosal injury and the likelihood of septal perforation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00368504251411215","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T17:36:31Z","timestamp":1766597791000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Impact of nasal septum deviation types on intraoperative mucoperichondrial perforation during septoplasty: A prospective cohort study"],"prefix":"10.1177","volume":"108","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8245-4166","authenticated-orcid":false,"given":"Sedat","family":"R\u00fczgar","sequence":"first","affiliation":[{"name":"Istanbul Ba\u011fc\u0131lar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5835-1044","authenticated-orcid":false,"given":"Alper","family":"Tabaru","sequence":"additional","affiliation":[{"name":"University of Health Sciences"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,24]]},"reference":[{"key":"e_1_3_2_2_2","volume-title":"StatPearls [Internet]","author":"Watters C","unstructured":"Watters C, Brar S, Yapa S. Septoplasty. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing, 2025 Jan. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK567718\/ (accessed 13 November 2025)."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30354-X"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.3310\/MVFR4028"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2023.103811"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2006-954847"},{"key":"e_1_3_2_7_2","volume-title":"StatPearls [Internet]","author":"Downs BW","unstructured":"Downs BW, Sauder HM. Septal perforation. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing, 2025 Jan. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK537208\/ (accessed 13 November 2025)."},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-06887-2"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/ohbm5020014"},{"key":"e_1_3_2_10_2","article-title":"Nasal septal deviation: a comprehensive narrative review","volume":"14","author":"Alghamdi FS","year":"2022","unstructured":"Alghamdi FS, Albogami D, Alsurayhi AS, et al. Nasal septal deviation: a comprehensive narrative review. Cureus 2022; 14: e31317.","journal-title":"Cureus"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.5152\/balkanmedj.2015.159957"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2024.101464"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2016.03.015"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2007.11.008"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ohn.918"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.5999\/aps.2020.02033"},{"key":"e_1_3_2_17_2","first-page":"295","article-title":"A hospital-based retrospective assessment of deviated nasal septum based on Mladina\u2019s classification and its association with symptomatology and post-septoplasty complications","volume":"13","author":"Haque MT","year":"2023","unstructured":"Haque MT, Kumar M, Sharma S. A hospital-based retrospective assessment of deviated nasal septum based on Mladina\u2019s classification and its association with symptomatology and post-septoplasty complications. Int J Toxicol Pharmacol Res 2023; 13: 295\u2013299.","journal-title":"Int J Toxicol Pharmacol Res"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-023-04029-0"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-018-4990-8"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2022.12.010"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-019-05393-w"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1990-2818"},{"key":"e_1_3_2_23_2","first-page":"390","article-title":"Risk factors for nasal septal perforation after septoplasty","volume":"3","author":"Y\u0131ld\u0131z E","year":"2019","unstructured":"Y\u0131ld\u0131z E, Ulu S, Kahveci OK. Risk factors for nasal septal perforation after septoplasty. 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