{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:58:44Z","timestamp":1790747924003,"version":"4.1.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>Venous arterialization has emerged as a limb-salvage option for selected patients with no-option chronic limb-threatening ischemia, particularly those with type 2 diabetes, extensive pedal occlusive disease, and small artery disease (distal tibial and inframalleolar disease) in whom conventional bypass or endovascular revascularization is not an option. We present a case of a man in his late 70s with diabetes and severe distal occlusive disease who underwent endovascular venous arterialization for a threatened limb with gangrene, followed by staged wound reconstruction after open transmetatarsal amputation. Reconstruction was performed in a stepwise manner with serial debridement and wound-bed preparation, application of an Integra dermal regeneration template to augment granulation tissue formation, and subsequent Meek fractional skin grafting for definitive coverage. The wound healed over approximately 7 months, and the patient regained the ability to ambulate. This case highlights the concept that venous arterialization should be viewed not as an isolated revascularization maneuver, but as the perfusion-enabling stage of a broader reconstructive pathway in no-option limb salvage.<\/jats:p>","DOI":"10.1177\/00368504261477986","type":"journal-article","created":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T13:08:34Z","timestamp":1787231314000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Staged matrix and micrografting reconstruction for no-option CLTI: A case report"],"prefix":"10.1177","volume":"109","author":[{"given":"Dimitrios","family":"Miserlis","sequence":"first","affiliation":[{"name":"University of Texas at San Antonio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas","family":"Ferrer","sequence":"additional","affiliation":[{"name":"Cardiovascular Associates of West 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