{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:59:17Z","timestamp":1790747957293,"version":"4.1.0"},"reference-count":26,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To investigate the association between the hemoglobin-to-red cell distribution width ratio (HRR) and in-hospital and 30-day mortality among critically ill patients with atrial fibrillation (AF).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study of AF patients from the MIMIC-III and IV databases. Patients were divided into HRR quartiles. The primary outcomes were in-hospital and 30-day mortality. Kaplan-Meier survival curves, dose-response analysis, and multivariable regression models assessed HRR-mortality associations, with subgroup and sensitivity analyses for robustness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 21,625 patients (median age 75.0 years, 59.8% male), in-hospital and 30-day mortality rates were 14.8% and 24.5%. Mortality was inversely related to HRR, with Q1 showing higher risk than Q4 (in-hospital: 20.0% vs. 12.7%). Dose-response analysis revealed linear HRR-mortality relationships. In adjusted models, each 0.1-unit HRR increase reduced risk by 37% for in-hospital mortality (OR: 0.63, 95% CI: 0.60-0.66) and 31% for 30-day mortality (HR: 0.69, 95% CI: 0.67-0.71). Compared with Q1, Q4 was associated with 79% lower adjusted odds of in-hospital mortality and a 71% lower adjusted hazard of 30-day mortality. Subgroup analyses confirmed consistent protective associations, with modification by age and myocardial infarction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Higher HRR was independently associated with lower in-hospital and 30-day mortality in critically ill patients with atrial fibrillation. Higher HRR associates with improved survival, supporting its potential role as a complementary marker for risk assessment and prognostic evaluation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00368504261484901","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T03:48:25Z","timestamp":1788925705000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between hemoglobin-to-red cell distribution width ratio and critically ill patients with atrial fibrillation: A retrospective cohort study"],"prefix":"10.1177","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4092-0322","authenticated-orcid":false,"given":"Yuting","family":"Yuan","sequence":"first","affiliation":[{"name":"Capital Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijuan","family":"Guo","sequence":"additional","affiliation":[{"name":"Peking University International Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9265-0160","authenticated-orcid":false,"given":"Xinghe","family":"Sun","sequence":"additional","affiliation":[{"name":"Peking University International Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,8]]},"reference":[{"key":"e_1_3_8_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/1747493019897870"},{"key":"e_1_3_8_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.595140"},{"key":"e_1_3_8_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2011.10.011"},{"key":"e_1_3_8_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000140263.20897.42"},{"key":"e_1_3_8_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc9057"},{"key":"e_1_3_8_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-025-07895-0"},{"key":"e_1_3_8_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2024.103794"},{"key":"e_1_3_8_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-022-02194-w"},{"key":"e_1_3_8_10_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.726025"},{"key":"e_1_3_8_11_2","doi-asserted-by":"publisher","DOI":"10.3109\/10408363.2014.992064"},{"key":"e_1_3_8_12_2","doi-asserted-by":"publisher","DOI":"10.5858\/133.4.628"},{"key":"e_1_3_8_13_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-025-04673-0"},{"key":"e_1_3_8_14_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/7141216"},{"key":"e_1_3_8_15_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11030886"},{"key":"e_1_3_8_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2023.131556"},{"key":"e_1_3_8_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2023.131368"},{"key":"e_1_3_8_18_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcdd9110400"},{"key":"e_1_3_8_19_2","doi-asserted-by":"publisher","DOI":"10.1038\/sdata.2016.35"},{"key":"e_1_3_8_20_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41597-023-02136-9"},{"key":"e_1_3_8_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.22530"},{"key":"e_1_3_8_22_2","doi-asserted-by":"publisher","DOI":"10.1093\/jamia\/ocx084"},{"key":"e_1_3_8_23_2","first-page":"1","article-title":"mice: Multivariate Imputation by Chained Equations in R","volume":"45","author":"van Buuren S","year":"2011","unstructured":"van Buuren S, Groothuis-Oudshoorn K. mice: Multivariate Imputation by Chained Equations in R. Journal of Statistical Software 2011; 45: 1\u201367. https:\/\/doi.org\/10.18637\/jss.v045.i03","journal-title":"Journal of Statistical Software"},{"key":"e_1_3_8_24_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-8-200710160-00010"},{"key":"e_1_3_8_25_2","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2025.1534479"},{"key":"e_1_3_8_26_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12872-025-04632-9"},{"key":"e_1_3_8_27_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-92228-w"}],"container-title":["Science Progress"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00368504261484901","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00368504261484901","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00368504261484901","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:20:43Z","timestamp":1790745643000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00368504261484901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":26,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10.1177\/00368504261484901"],"URL":"https:\/\/doi.org\/10.1177\/00368504261484901","relation":{},"ISSN":["0036-8504","2047-7163"],"issn-type":[{"value":"0036-8504","type":"print"},{"value":"2047-7163","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"article-number":"00368504261484901"}}