{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,25]],"date-time":"2026-10-25T08:37:31Z","timestamp":1792917451881,"version":"4.5.0"},"reference-count":24,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Science Progress"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To compare the pregnancy outcomes following amniocentesis in twin pregnancies conceived with assisted reproduction technology (ART) versus spontaneously conceived twins.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective study, the 40case records of twin pregnancies in which amniocentesis was performed at HuizhouCentral People\u2019s Hospital between 2021 and 2024 were reviewed. Pregnancy outcomes and neonatal outcomes of twin pregnancies were compared between the ART group (n = 25)and spontaneous twin pregnancy group(n = 15).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There was no statistically significant difference in pregnancy loss rate between the groups(4.00% vs. 6.67%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 1.000). The pregnancy loss rate before 24 weeks of gestation in the two groups were 4.00% and 6.67%, respectively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 1.000). No pregnancy loss occurred within 4 weeks after the amniocentesis in bothgroup. The preterm birthrate before 37weeks of gestation in the two groups were 76.00% and 46.67%, respectively, and showed no significant difference (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.089).There were significant differences between-group in birth weight and Apgar score at 10 min (both\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05), while there were no significant differences in low birth weight (&lt;2500 g), Apgar score at 1 min, Apgar score at 5 min, and neonatal\/pediatric department transfer (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>No statistically significant increase in the risk of pregnancy loss after amniocentesis was observed among ART-conceived twin pregnancies compared with spontaneously conceived twin pregnancies.However, they should not be interpreted as evidence of equivalence or absence of a clinically meaningful difference.Given the limited sample size, these findings should be confirmed in larger, multicenter studies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00368504261499296","type":"journal-article","created":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:26:51Z","timestamp":1792690011000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Pregnancy outcomes after amniocentesis in ART-Conceived versus spontaneously conceived twin pregnancies: A single-center retrospective study"],"prefix":"10.1177","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-9932-771X","authenticated-orcid":false,"given":"Weixia","family":"Weng","sequence":"first","affiliation":[{"name":"Prenatal Diagnosis Department, Huizhou Central people\u2019s Hospital, Huizhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Lu","sequence":"additional","affiliation":[{"name":"Prenatal Diagnosis Department, Huizhou Central people\u2019s Hospital, Huizhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6040-4886","authenticated-orcid":false,"given":"Chunyan","family":"Wang","sequence":"additional","affiliation":[{"name":"Huizhou Central people\u2019s Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Ji","sequence":"additional","affiliation":[{"name":"Prenatal Diagnosis Department, Huizhou Central people\u2019s Hospital, Huizhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,10,22]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deab029"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)01295-2"},{"key":"e_1_3_6_4_2","first-page":"1070","article-title":"Fertility treatments and multiple births in the United States","volume":"370","author":"Kulkarni AD","year":"2014","unstructured":"Kulkarni AD, Kissin DM, Adashi EY. 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