{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:03:00Z","timestamp":1777899780768,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scott Med J"],"published-print":{"date-parts":[[2005,5]]},"abstract":"<jats:p>Background: We aimed to study the timing of aspirin prescription in ischaemic stroke comparing patients admitted to an acute stroke unit (ASU) directly or via a general medical ward. We also analysed prescription of secondary preventive therapies in stroke patients in an ASU. Methods: Retrospective analysis was made of medical notes and prescription records of 69 patients admitted to an ASU over a three month period to establish timing of aspirin prescription with respect to onset of stroke symptoms, CT brain scan and route of admission to the ASU. Results: CT brain scans were obtained at a median of 2.1 days post stroke (IQ range 1.3\u20134.3). Patients directly admitted to the ASU received aspirin earlier post admission compared to those admitted via a medical ward (0.7 vs 2.2 days, p&lt;0.01) and were also more likely to receive aspirin prior to CT scan being performed (57% vs 19%, p=0.02). 86% of stroke patients were discharged on an antiplatelet therapy, 79% on a statin, 37% on a thiazide diuretic and 32% on an ACE inhibitor or angiotensin II antagonist. Conclusion: Aspirin was given more promptly in acute stroke and more commonly prior to CT scanning in an ASU compared to a medical ward. Statin therapy is used extensively in stroke but there is a much lower rate of initiation of other secondary preventive therapies (e.g. anti-hypertensive therapy) in hospital. These findings demonstrate a hesitancy in early use of aspirin amongst general physicians and lends support for the use of stroke units.<\/jats:p>","DOI":"10.1177\/003693300505000209","type":"journal-article","created":{"date-parts":[[2017,1,10]],"date-time":"2017-01-10T17:30:28Z","timestamp":1484069428000},"page":"69-72","source":"Crossref","is-referenced-by-count":1,"title":["Timing of Aspirin and Secondary Preventative Therapies in Acute Stroke: Support for Use of Stroke Units"],"prefix":"10.1177","volume":"50","author":[{"given":"J","family":"Reid","sequence":"first","affiliation":[{"name":"Aberdeen Royal Infirmary, Foresterhill, Aberdeen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M-J","family":"MacLeod","sequence":"additional","affiliation":[{"name":"Aberdeen Royal Infirmary, Foresterhill, Aberdeen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Williams","sequence":"additional","affiliation":[{"name":"Aberdeen Royal Infirmary, Foresterhill, Aberdeen"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2005,5,1]]},"reference":[{"key":"bibr1-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000064841.47697.22"},{"key":"bibr2-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.31.6.1240"},{"key":"bibr3-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.324.7329.71"},{"key":"bibr4-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)04010-5"},{"key":"bibr5-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)04011-7"},{"key":"bibr6-003693300505000209","unstructured":"National Clinical Guidelines for stroke, second edition (June 2004), prepared by The Intercollegiate Working Party for Stroke, Royal College of Physicians, UK."},{"key":"bibr7-003693300505000209","volume-title":"In: The Cochrane Library, Issue","volume":"2","author":"Sandercock P","year":"2004"},{"key":"bibr8-003693300505000209","first-page":"127","volume":"5","author":"Gubitz G.","journal-title":"Clinical Evidence"},{"key":"bibr9-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.23.2981"},{"key":"bibr10-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200001203420301"},{"key":"bibr11-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(01)06178-5"},{"key":"bibr12-003693300505000209","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200225130-00005"},{"key":"bibr13-003693300505000209","volume-title":"In: The Cochrane Library, Issue","volume":"3","author":"Stroke Unit Trialists' Collaboration","year":"2000"},{"key":"bibr14-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jhh.1001523"},{"key":"bibr15-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)93206-O"},{"key":"bibr16-003693300505000209","unstructured":"Management of Patients with Stroke, A national Clinical Guideline recommended for use in Scotland by the Scottish Intercollegiate Guidelines Network. SIGN publication no. 13. Edinburgh; May 1997."},{"key":"bibr17-003693300505000209","doi-asserted-by":"publisher","DOI":"10.3310\/hta8010"},{"key":"bibr18-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.70.821.185"},{"key":"bibr19-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7354.17"},{"issue":"7","key":"bibr20-003693300505000209","first-page":"1699","volume":"34","author":"Schrader J","year":"2003","journal-title":"The ACCESS Study: evaluation of Acute Candesartan Cilexetil Therapy in Stroke Survivors. Stroke."},{"key":"bibr21-003693300505000209","first-page":"P132","volume":"16","author":"Razvi S.S.M.","year":"2003","journal-title":"Cerbrovasc. Dis."},{"issue":"5","key":"bibr22-003693300505000209","first-page":"562","volume":"15","author":"Rudd AG","year":"2001","journal-title":"Royal College of Physicians Intercollegiate Stroke Working Party. Clin Rehabil."},{"key":"bibr23-003693300505000209","doi-asserted-by":"publisher","DOI":"10.1159\/000068207"}],"container-title":["Scottish Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/003693300505000209","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/003693300505000209","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T10:14:21Z","timestamp":1777630461000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/003693300505000209"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["10.1177\/003693300505000209"],"URL":"https:\/\/doi.org\/10.1177\/003693300505000209","relation":{},"ISSN":["0036-9330","2045-6441"],"issn-type":[{"value":"0036-9330","type":"print"},{"value":"2045-6441","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,5]]}}}