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As much as possible, efforts were made to focus on studies where polymyalgia rheumatica and giant cell arteritis were treated as separate entities. The selection of articles was influenced by the authors' bias that polymyalgia rheumatica is a separate clinical condition from giant cell arteritis and that, as yet, the diagnosis is a clinical one. Apart from the elevation of circulating acute phase proteins, which has been recognised as a feature of polymyalgia rheumatica for over 60 years, the diagnosis receives no significant help from the laboratory or from diagnostic imaging.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>This review has shown that, following the recognition of polymyalgia as a distinct clinical problem of the elderly, the results of a considerable amount of research efforts including those using the advances in clinical imaging technology over the past 60 years, have done little to change the ability of clinicians to define the disease more accurately. Since the introduction of corticosteroids in the 1950s, there has been also very little change in the clinical management of the condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Polymyalgia rheumatica remains a clinical enigma, and its relationship to giant cell arteritis is no clearer now than it has been for the past 125 years. Diagnosing this disease is still almost exclusively dependent on the clinical acumen of a patient\u2019s medical attendant. Until an objective method of identifying it clearly in the clinical setting is available, uncovering the aetiology is still unlikely, and until then, preventing the pain and stiffness of the disease while avoiding the problems of prolonged exoposure to corticosteroids is likely to remain elusive or serendipitous.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0036933014548144","type":"journal-article","created":{"date-parts":[[2014,9,8]],"date-time":"2014-09-08T21:56:54Z","timestamp":1410213414000},"page":"220-228","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Polymyalgia rheumatica: 125 years of progress?"],"prefix":"10.1177","volume":"59","author":[{"given":"Patrick J","family":"Rooney","sequence":"first","affiliation":[{"name":"Professor of Medicine, Department of Clinical Skills, St George\u2019s University, Grenada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer","family":"Rooney","sequence":"additional","affiliation":[{"name":"Associate Professor of Medicine, Department of Clinical Skills, St George\u2019s University, Grenada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geza","family":"Balint","sequence":"additional","affiliation":[{"name":"Consultant Rheumatologist, National Institute of Rheumatology and Physiotherapy, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Balint","sequence":"additional","affiliation":[{"name":"Head of Department and Consultant Rheumatologist, 3rd Department of Rheumatology, National Institute of Rheumatology and Physiotherapy, Hungary"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,9,7]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.1450.811"},{"key":"e_1_3_3_3_2","first-page":"29","article-title":"Dr William Bruce (1835 \u2013 1920), the Scottish highland spa at Strathpeffer and a possible description of polymyalgia rheumatica","volume":"33","author":"Buchanan WW","year":"2003","unstructured":"Buchanan WW, Kean W. 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