{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:05:10Z","timestamp":1777899910706,"version":"3.51.4"},"reference-count":15,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scott Med J"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:p>This study aims to determine therapeutic effect of hemoperfusion on patients with acute toxic encephalopathy induced by silkworm chrysalis ingestion. Three patients who developed toxic encephalopathy after chrysalis ingestion were analysed. Two patients lost their consciousness, while two patients had typical extrapyramidal tremor symptoms. Further neurological examination revealed various degrees of muscle strength impairment in these patients. All of them received treatments of omeprazole (40\u2009mg\/day), furosemide (one dose of 20\u2009mg), vitamin C (2.0\u2009g\/day), calcium gluconate (2.0\u2009g\/day) and rehydration with glucose and sodium chloride (1500\u2009ml\/day). In addition, they received hemoperfusion treatment for 1.5\u2009h. All patients recovered well after hemoperfusion. Two patients with loss of consciousness significantly recovered at 45\u2009min and 65\u2009min after hemoperfusion, respectively. All tremor symptoms were completely resolved in these patients at 30\u2009min, 50\u2009min, and 70\u2009min following treatment, respectively. After the hemoperfusion treatment, encephalopathy symptoms of two patients had completely disappeared. All patients were followed up for one month and did not report any abnormalities. Our study indicates that hemoperfusion could be a useful and efficient treatment strategy for patients with acute encephalopathy after silkworm chrysalis ingestion. Larger clinical trials with longer follow-up are warranted to confirm the clinical benefit of hemoperfusion.<\/jats:p>","DOI":"10.1177\/0036933015619291","type":"journal-article","created":{"date-parts":[[2015,11,26]],"date-time":"2015-11-26T22:49:28Z","timestamp":1448578168000},"page":"149-154","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The effect of hemoperfusion on patients with toxic encephalopathy induced by silkworm chrysalis ingestion"],"prefix":"10.1177","volume":"61","author":[{"given":"Haixia","family":"Hu","sequence":"first","affiliation":[{"name":"Attending doctor, Department of Emergency Medicine, The First Affiliated Hospital of Jilin University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Wang","sequence":"additional","affiliation":[{"name":"Attending doctor, Department of Neurology, The First Affiliated Hospital of Jilin University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaqi","family":"Lv","sequence":"additional","affiliation":[{"name":"Resident physician, Department of Emergency Medicine, The First Affiliated Hospital of Jilin University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jing","family":"Sun","sequence":"additional","affiliation":[{"name":"Resident physician, Department of Emergency Medicine, The First Affiliated Hospital of Jilin University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jihong","family":"Xing","sequence":"additional","affiliation":[{"name":"Professor, Department of Emergency Medicine, The First Affiliated Hospital of Jilin University, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoliang","family":"Liu","sequence":"additional","affiliation":[{"name":"Professor, Department of Emergency Medicine, The First Affiliated Hospital of Jilin University, 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