{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T04:50:35Z","timestamp":1781067035291,"version":"3.54.1"},"reference-count":24,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T00:00:00Z","timestamp":1520380800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scott Med J"],"published-print":{"date-parts":[[2018,5]]},"abstract":"\n Background and aims<\/jats:title>\n Novel psychoactive substances are compounds intended to mimic the effects of illicit drugs. They provide a unique challenge to healthcare, as complications of their use and their impact on services are relatively unknown. This study aims to determine nature of presentations, patient demographics and impact on healthcare.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Novel psychoactive substances users who presented to a large urban emergency department over 4 weeks were prospectively identified and followed for 1 year. Patients over 13 years old were eligible for inclusion. Information regarding patient demographics and presentations was collected.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n During the study period, 53 patients (39 male), mean age 32.6\u2009\u00b1\u20098.9 (\u00b1standard deviation), presented 148 times with complaints relating to novel psychoactive substances use. Study population characteristics included history of illicit drug use (83.0%), intravenous drug use (64.2%), psychiatric diagnosis or symptoms (56.6%), methadone prescription (52.8%) and having no fixed abode (37.7%). Injection was the most common method of use (72.3%), Burst the most commonly named agent (19.6%) and behavioural change the most common presenting complaint (31.1%). Patients collectively spent 10,620 h in hospital over 1 year.<\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n This study highlights differences between the young population targeted by government campaigns regarding novel psychoactive substances use and the presenting population to hospital, and the associated burden on the National Health Service.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/0036933018760761","type":"journal-article","created":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T01:53:04Z","timestamp":1520473984000},"page":"39-44","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["A prospective observational study of emergency department presentations following novel psychoactive substance use"],"prefix":"10.1177","volume":"63","author":[{"given":"David E","family":"Henshall","sequence":"first","affiliation":[{"name":"Medical Student, University of Edinburgh Medical School, Royal Infirmary of Edinburgh Emergency Department, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Callum WD","family":"Innes","sequence":"additional","affiliation":[{"name":"Medical Student, University of Edinburgh Medical School, Royal Infirmary of Edinburgh Emergency Department, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott R","family":"Morrison","sequence":"additional","affiliation":[{"name":"Medical Student, University of Edinburgh Medical School, Royal Infirmary of Edinburgh Emergency Department, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Blair","family":"Wilson","sequence":"additional","affiliation":[{"name":"Medical Student, University of Edinburgh Medical School, Royal Infirmary of Edinburgh Emergency Department, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan A","family":"Brown","sequence":"additional","affiliation":[{"name":"Medical Student, University of Edinburgh Medical School, Royal Infirmary of Edinburgh Emergency Department, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shannon M","family":"McAllister","sequence":"additional","affiliation":[{"name":"Medical Student, University of Edinburgh Medical School, Royal Infirmary of Edinburgh Emergency Department, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seamus L","family":"Culshaw","sequence":"additional","affiliation":[{"name":"Medical Student, University of Edinburgh Medical School, Royal Infirmary of Edinburgh Emergency Department, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaina","family":"Reda","sequence":"additional","affiliation":[{"name":"Medical Student, University of Edinburgh Medical School, Royal Infirmary of Edinburgh Emergency Department, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,3,7]]},"reference":[{"key":"bibr1-0036933018760761","unstructured":"Fraser F.\n New psychoactive substances \u2013 Evidence review\n . Scottish Government, Edinburgh, 2014."},{"key":"bibr2-0036933018760761","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2013.09.026"},{"key":"bibr3-0036933018760761","unstructured":"British Home Office.\n Guidance for local authorities on taking action against \u2018head shops\u2019 selling new psychoactive substances\u2009-\u2009working with local partners\n . Home Office, London, 2015."},{"key":"bibr4-0036933018760761","unstructured":"European Monitoring Centre for Drugs and Drug Addiction.\n New psychoactive substances in Europe. An update from the EU early warning system (March 2015)\n . Luxembourg, Publications Office of the European Union, 2015."},{"key":"bibr5-0036933018760761","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3223-14.2014"},{"key":"bibr6-0036933018760761","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcq132"},{"key":"bibr7-0036933018760761","unstructured":"United Nations Office on Drugs and Crime.\n World drug report 2013\n . Vienna, United Nations, 2013."},{"key":"bibr8-0036933018760761","doi-asserted-by":"publisher","DOI":"10.1186\/s13722-015-0024-7"},{"key":"bibr9-0036933018760761","unstructured":"Edinburgh Emergency Medicine. Royal Infirmary of Edinburgh Emergency Department. Edinburgh, UK, https:\/\/www.edinburghemergencymedicine.com\/rie\/, 2017."},{"key":"bibr10-0036933018760761","unstructured":"My Crew.\n Drugs information\n . My Crew, Edinburgh, 2015."},{"key":"bibr11-0036933018760761","unstructured":"Home Office.\n Circular 015\/2015: temporary control of 5 methylphenidate-based NPS\n . Home Office, London, 2015."},{"key":"bibr12-0036933018760761","unstructured":"Home Office.\n Circular 028\/2015: Misuse of Drugs Act 1971 (Temporary Class Drug) (No.3) Order 2015 (S.I. 2015\/1929)\n . 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