{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T18:07:05Z","timestamp":1779818825880,"version":"3.53.1"},"reference-count":19,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Scott Med J"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Transient isolated right ventricular hypertrophy (RVH) is an infrequently recognized cause of early neonatal cyanosis and prolonged oxygen requirement, closely mimicking cyanotic congenital heart disease or persistent pulmonary hypertension of the newborn.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We present a narrative review of published neonatal cases of transient isolated RVH and describe illustrative observations from four term neonates managed at a tertiary neonatal unit over a 3-year period. Clinical features, antenatal exposures, echocardiographic findings, management, and outcomes were reviewed. A focused literature search identified previously reported neonatal cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Including the present cohort, 18 neonatal cases have been described to date. Most neonates presented within the first day of life with cyanosis. Echocardiography demonstrated isolated RVH with preserved biventricular function and absence of structural heart disease; premature ductal closure was documented in several cases. Identified risk factors included fetal or perinatal distress, maternal exposure to nonsteroidal anti-inflammatory drugs or corticosteroids, maternal diabetes, and polyphenol-rich substances. Clinical improvement occurred with supportive care, and follow-up echocardiography showed regression of RVH within 4\u201312 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Transient isolated RVH represents a benign, self-limiting cause of early neonatal cyanosis. Awareness of this phenotype and its natural history may help avoid unnecessary investigations\/interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00369330261421354","type":"journal-article","created":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T17:59:43Z","timestamp":1771523983000},"page":"76-84","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Transient isolated right ventricular hypertrophy: A benign phenotype in neonates: Case series and review of the literature"],"prefix":"10.1177","volume":"71","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1465-4203","authenticated-orcid":false,"given":"Swasthi Kabi","family":"Satpathy","sequence":"first","affiliation":[{"name":"Department of Neonatology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6292-110X","authenticated-orcid":false,"given":"Choudri Muzafar","family":"Paswal","sequence":"additional","affiliation":[{"name":"Department of Neonatology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8456-1133","authenticated-orcid":false,"given":"Sushil Kumar","family":"Choudhary","sequence":"additional","affiliation":[{"name":"Department of Neonatology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6660-5219","authenticated-orcid":false,"given":"Neeraj","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Neonatology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0157-4300","authenticated-orcid":false,"given":"Arun Kumarendu","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Neonatology, All India Institute of Medical Sciences, Jodhpur, Jodhpur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,2,19]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951103000799"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.23937\/2378-2951\/1410050"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF02730827"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.4103\/2249-4847.140405"},{"key":"e_1_3_3_6_2","first-page":"370","article-title":"In utero premature closure of the ductus arteriosus presenting as isolated RVH","volume":"108","author":"Long WE","year":"2009","unstructured":"Long WE, Wilson AD, Srinivasan S, et al. In utero premature closure of the ductus arteriosus presenting as isolated RVH. Wis Med J 2009; 108: 370\u2013372.","journal-title":"Wis Med J"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1038"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.12956\/tjpd.2013.14"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.2459\/01.JCM.0000263503.83484.bb"},{"key":"e_1_3_3_10_2","first-page":"593","article-title":"Transient isolated right ventricular hypertrophy in a neonate","volume":"69","author":"Ilhan O","year":"2022","unstructured":"Ilhan O, Akbay SA, Ozdemir SA, et al. Transient isolated right ventricular hypertrophy in a neonate. 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