{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:29:44Z","timestamp":1777901384339,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1984,7,1]],"date-time":"1984-07-01T00:00:00Z","timestamp":457488000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scott Med J"],"published-print":{"date-parts":[[1984,7]]},"abstract":"<jats:p>Trabecular bone volume, forming surface and percent surface resorption have been determined in iliac crest samples obtained post mortem from 43 young men and 49 elderly men and in biopsies obtained from 22 males with spinal osteoporosis. The mean bone volume was significantly lower in the old than in the young controls and significantly lower again in the osteoporotic cases. Forming surfaces were significantly lower in the old than the young controls but were not different as between old controls and cases of osteoporosis. Percent surface resorption was the same in young and old controls but significantly increased in the osteoporotics. Multiple regression analysis showed that trabecular bone volume was a significant positive function of forming surface and a significant inverse function of fractional surface resorption. Age-related (simple) osteoporosis in men appears to be due to reduced bone formation whereas pathological (accelerated) osteoporosis is due to increased bone resorption.<\/jats:p>","DOI":"10.1177\/003693308402900307","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T13:51:24Z","timestamp":1484142684000},"page":"171-175","source":"Crossref","is-referenced-by-count":20,"title":["Bone Formation and Resorption as the Determinants of Trabecular Bone Volume in Normal and Osteoporotic Men"],"prefix":"10.1177","volume":"29","author":[{"given":"B. E. C.","family":"Nordin","sequence":"first","affiliation":[{"name":"M.R.C. Mineral Metabolism Unit, The General Infirmary, Great George Street, Leeds"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Aaron","sequence":"additional","affiliation":[{"name":"M.R.C. Mineral Metabolism Unit, The General Infirmary, Great George Street, Leeds"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Speed","sequence":"additional","affiliation":[{"name":"M.R.C. Mineral Metabolism Unit, The General Infirmary, Great George Street, Leeds"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. M.","family":"Francis","sequence":"additional","affiliation":[{"name":"M.R.C. Mineral Metabolism Unit, The General Infirmary, Great George Street, Leeds"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Makins","sequence":"additional","affiliation":[{"name":"M.R.C. Mineral Metabolism Unit, The General Infirmary, Great George Street, Leeds"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1984,7,1]]},"reference":[{"key":"bibr1-003693308402900307","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1941.02820220007002"},{"key":"bibr2-003693308402900307","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(65)90109-9"},{"key":"bibr3-003693308402900307","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5749.571"},{"key":"bibr4-003693308402900307","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-595X(73)80046-5"},{"key":"bibr5-003693308402900307","first-page":"298","volume-title":"Calcium, Phosphate and Magnesium Metabolism","author":"Aaron JE","year":"1976"},{"key":"bibr6-003693308402900307","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)90526-2"},{"key":"bibr7-003693308402900307","unstructured":"Meunier PJ, Sellami S, Briancon D, Edouard C. Histological heterogeneity of apparently idiopathic osteoporosis. In: DeLuca HF, Frost HM, Jee WSS, Johnston CCJr, Parfitt AM. eds. Osteoporosis: Recent Advances in Pathogenesis and Treatment. Baltimore: University Park Press 1981: 293\u2013301."},{"key":"bibr8-003693308402900307","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-595X(81)80041-2"},{"key":"bibr9-003693308402900307","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(74)90850-X"},{"key":"bibr10-003693308402900307","first-page":"359","volume-title":"Osteoporosis: Recent advances in Pathogenesis and Treatment","author":"Nordin BEC","year":"1981"},{"key":"bibr11-003693308402900307","unstructured":"Horsman A, Nordin BEC, Aaron J, Marshall DH. Cortical and trabecular osteoporosis and their relation to fractures in the elderly. In: DeLuca HF, Frost HM, Jee WSS, Johnston CCJr, Parfitt AM. Osteoporosis: Recent Advances in Pathogenesis and Treatment. Baltimore: University Park Press 1981: 175\u2013184."},{"key":"bibr12-003693308402900307","doi-asserted-by":"publisher","DOI":"10.1007\/BF02064074"}],"container-title":["Scottish Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/003693308402900307","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/003693308402900307","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:00:08Z","timestamp":1777633208000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/003693308402900307"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,7]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1984,7]]}},"alternative-id":["10.1177\/003693308402900307"],"URL":"https:\/\/doi.org\/10.1177\/003693308402900307","relation":{},"ISSN":["0036-9330","2045-6441"],"issn-type":[{"value":"0036-9330","type":"print"},{"value":"2045-6441","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,7]]}}}