{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T13:30:48Z","timestamp":1777901448693,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1986,10,1]],"date-time":"1986-10-01T00:00:00Z","timestamp":528508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Scott Med J"],"published-print":{"date-parts":[[1986,10]]},"abstract":"<jats:p>\n                    Twenty-two patients with idiopathic thrombocytopenic purpura were treated with high-dose intravenous immunoglobulin infusions using an intact intravenous immunoglobulin preparation and a product designed for intramuscular administration. Seventeen patients (77%) responded favourably (rise in platelet count to 100 \u00d7 10\n                    <jats:sup>9<\/jats:sup>\n                    \/1 or above). Children responded better than the adults, and the acute cases better than the chronic. Splenectomy and the presence of detectable platelet antibody had no effect on the response rate. Both products induced identical responses.\n                  <\/jats:p>","DOI":"10.1177\/003693308603100404","type":"journal-article","created":{"date-parts":[[2017,1,11]],"date-time":"2017-01-11T10:31:02Z","timestamp":1484130662000},"page":"231-233","source":"Crossref","is-referenced-by-count":2,"title":["Intravenous Immunoglobulin Therapy for Idiopathic Thrombocytopenic Purpura"],"prefix":"10.1177","volume":"31","author":[{"given":"H.I.","family":"Atrah","sequence":"first","affiliation":[{"name":"Glasgow and West of Scotland Blood Transfusion Service, Regional Laboratories, Law Hospital, Carluke"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.J.","family":"Crawford","sequence":"additional","affiliation":[{"name":"Glasgow and West of Scotland Blood Transfusion Service, Regional Laboratories, Law Hospital, Carluke"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.S.","family":"Gabra","sequence":"additional","affiliation":[{"name":"Glasgow and West of Scotland Blood Transfusion Service, Regional Laboratories, Law Hospital, Carluke"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Glasgow and West of Scotland Blood Transfusion Service, Regional Laboratories, Law Hospital, Carluke"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1986,10,1]]},"reference":[{"key":"bibr1-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)92400-4"},{"key":"bibr2-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1984.tb01266.x"},{"key":"bibr3-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198205273062102"},{"key":"bibr4-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)91738-5"},{"key":"bibr5-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1007\/BF00320302"},{"key":"bibr6-003693308603100404","first-page":"193","volume":"2","author":"Salama A","year":"1983","journal-title":"Competitive inhibition of reticuloendothelial system function by sequestration of autologous red blood cells? Lancet"},{"key":"bibr7-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)91680-5"},{"key":"bibr8-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)92833-8"},{"key":"bibr9-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1978.tb01089.x"},{"key":"bibr10-003693308603100404","first-page":"587","volume":"1","author":"Leen CLS","year":"1985","journal-title":"Lancet"},{"key":"bibr11-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)90810-2"},{"key":"bibr12-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)90730-X"},{"key":"bibr13-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(85)91869-0"},{"key":"bibr14-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1985.tb07417.x"},{"key":"bibr15-003693308603100404","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)90701-3"},{"key":"bibr16-003693308603100404","unstructured":"Romer J, Spath PJ. Molecular composition of immunoglobulin preparations and its relation to complement activation. In Nydegger UE, ed. Immuno-haemotherapy: A guide to immunoglobulin prophylaxis and therapy. London: Academic Press 1982; 123\u2013130."}],"container-title":["Scottish Medical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/003693308603100404","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/003693308603100404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T11:01:43Z","timestamp":1777633303000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/003693308603100404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,10]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1986,10]]}},"alternative-id":["10.1177\/003693308603100404"],"URL":"https:\/\/doi.org\/10.1177\/003693308603100404","relation":{},"ISSN":["0036-9330","2045-6441"],"issn-type":[{"value":"0036-9330","type":"print"},{"value":"2045-6441","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,10]]}}}