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Previous works on the parallel simulations of large-scale epidemic were implemented on traditional general purpose CPU-based platforms or clusters. As more and more high-performance computation clusters are being built with so-called general-purpose graphics cards, this paper presents the implementation and optimization techniques for social contact network-based large-scale epidemic simulation on GPU clusters. Compared with previous works, this paper focuses on (1) how to efficiently implement the contact network-based parallel epidemic simulation on GPUs, and (2) how to hide communication latencies between processing nodes to improve scalability. Our proposed techniques are implemented and tested on a commodity cluster whose processing nodes are equipped with GPGPUs. The experimental results show that, for the simulation of 20 million individuals and 1.2 billion host contacts on 80 nodes, the execution on GPUs can achieve 7.4\u00d7\u221211.7\u00d7 speedup over the execution on CPUs.<\/jats:p>","DOI":"10.1177\/0037549713482026","type":"journal-article","created":{"date-parts":[[2013,4,19]],"date-time":"2013-04-19T01:15:10Z","timestamp":1366334110000},"page":"1154-1172","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Epidemic simulation of a large-scale social contact network on GPU clusters"],"prefix":"10.1177","volume":"89","author":[{"given":"Peng","family":"Zou","sequence":"first","affiliation":[{"name":"Key Laboratory, Academy of Equipment, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya-shuai","family":"L\u00fc","sequence":"additional","affiliation":[{"name":"Key Laboratory, Academy of Equipment, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling-da","family":"Wu","sequence":"additional","affiliation":[{"name":"Key Laboratory, Academy of Equipment, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-li","family":"Chen","sequence":"additional","affiliation":[{"name":"Science and Technology on Complex System Simulation Laboratory, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-ping","family":"Yao","sequence":"additional","affiliation":[{"name":"School of Computer Science, National University of Defense Technology, Changsha, Hunan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,4,18]]},"reference":[{"key":"bibr1-0037549713482026","doi-asserted-by":"publisher","DOI":"10.1109\/SC.2008.5214892"},{"key":"bibr2-0037549713482026","doi-asserted-by":"publisher","DOI":"10.1145\/508791.508819"},{"key":"bibr3-0037549713482026","doi-asserted-by":"publisher","DOI":"10.1038\/nature02541"},{"key":"bibr4-0037549713482026","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0706849105"},{"key":"bibr5-0037549713482026","doi-asserted-by":"publisher","DOI":"10.1109\/TSMCA.2005.851291"},{"issue":"3","key":"bibr6-0037549713482026","first-page":"42","volume":"292","author":"Barrett CL","year":"2003","journal-title":"Scientific American"},{"key":"bibr7-0037549713482026","first-page":"63","volume-title":"Proceedings of Western Multiconference on Health Sciences Simulation","author":"Hsieh JL","year":"2005"},{"key":"bibr8-0037549713482026","unstructured":"Huang CY, Sun CT, Hsieh JL, Lin H. 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