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We adopt hexahedral voxels to represent the physical model of soft tissue to improve the visual realistic quality and computing efficiency of deformation simulation. We also adopt the concept of free boundary to simulate soft tissue geometric characteristics more precisely during the deformation process and introduce asynchronous diffusion by using the mechanical energy of mass points to achieve realistic soft tissue deformation effects. In order to meet the requirement of real-time surgery simulation, we accelerate the soft tissue deformation by using OpenCL (Open Computing Language) and optimize the parallel computing process in several means. Experimental results have shown that the GPU-assisted energy asynchronous diffusion parallel computing model for soft tissue deformation simulation implements satisfactory effects on deformation in visual realistic and real-time quality.<\/jats:p>","DOI":"10.1177\/0037549714552708","type":"journal-article","created":{"date-parts":[[2014,10,14]],"date-time":"2014-10-14T00:07:29Z","timestamp":1413245249000},"page":"1199-1208","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["GPU-assisted energy asynchronous diffusion parallel computing model for soft tissue deformation simulation"],"prefix":"10.1177","volume":"90","author":[{"given":"Xiangyun","family":"Liao","sequence":"first","affiliation":[{"name":"School of Computer, Wuhan University, Wuhan, Hubei 430079, P.R. 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