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We propose the adoption of agent-based modeling and simulation techniques as built-in tools to dynamically monitor the state of patient health and provide recommendations for self-management. To demonstrate the feasibility of our proposal we focus on Type 1 diabetes mellitus as our case study, and provide simulation results where the dynamic evolution of signal parameters is shown in the case of healthy and Type 1 diabetes mellitus patients, focussing in particular on the beneficial effects that self-management interventions have on plasma glucose values. <\/jats:p>","DOI":"10.1177\/0037549717712605","type":"journal-article","created":{"date-parts":[[2017,6,26]],"date-time":"2017-06-26T14:41:22Z","timestamp":1498488082000},"page":"781-793","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Agent-based modeling for the self-management of chronic diseases: An exploratory study"],"prefix":"10.1177","volume":"93","author":[{"given":"Sara","family":"Montagna","sequence":"first","affiliation":[{"name":"Department of Computer Science and Engineering (DISI), Alma Mater Studiorum, Universit\u00e0 di Bologna, Cesena, Italy"}]},{"given":"Andrea","family":"Omicini","sequence":"additional","affiliation":[{"name":"Department of Computer Science and Engineering (DISI), Alma Mater Studiorum, Universit\u00e0 di Bologna, Cesena, Italy"}]}],"member":"179","published-online":{"date-parts":[[2017,6,26]]},"reference":[{"key":"bibr1-0037549717712605","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbi.2015.06.003"},{"key":"bibr2-0037549717712605","doi-asserted-by":"publisher","DOI":"10.1016\/j.dss.2014.06.001"},{"key":"bibr3-0037549717712605","doi-asserted-by":"publisher","DOI":"10.1007\/s10916\u2013010\u20139571\u20133"},{"key":"bibr4-0037549717712605","doi-asserted-by":"publisher","DOI":"10.3390\/s130505406"},{"key":"bibr5-0037549717712605","doi-asserted-by":"publisher","DOI":"10.1109\/TSMCC.2012.2215852"},{"volume-title":"Innovative care for chronic conditions: Organizing and delivering high quality care for chronic noncommunicable diseases in the Americas","year":"2013","author":"Barcel\u00f3 A","key":"bibr6-0037549717712605"},{"key":"bibr7-0037549717712605","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.20.4.568"},{"key":"bibr8-0037549717712605","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17277-2"},{"key":"bibr9-0037549717712605","first-page":"94","volume":"2010","author":"Akter S","year":"2010","journal-title":"IMIA Yearb Med Inform"},{"key":"bibr10-0037549717712605","doi-asserted-by":"publisher","DOI":"10.1258\/jtt.2010.004017"},{"key":"bibr11-0037549717712605","volume-title":"Textbook of medical physiology","author":"Guyton AC","year":"2006","edition":"11"},{"key":"bibr12-0037549717712605","unstructured":"Montagna S, Omicini A, Angeli FD, et al. 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