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Great efforts have been made toward the simulation of multi-physics coupling processes in reactors. The interpretations of many terms that describe multi-physics simulation vary in different literatures. We organize and discuss some important terms relevant to the multi-physics coupling simulation. We compare the three most frequently used multi-physics coupling strategies: the operator splitting, Picard iteration, and Jacobian-Free Newton\u2013Krylov methods. We summarize three main viewpoints on the degree of coupling of the three strategies (loose, tight, or full coupling). Then we review the coupling software and corresponding coupling strategies in some representative virtual reactor projects. We present the research focuses of Spider coupling platform. The Spider is developed in the China Virtual Reactor (CVR) project. The multi-physics phenomena are considered in the CVR project from three scales: fuel scale, reactor core scale, and system scale. Both loose and tight coupling strategies are supported in the Spider platform.<\/jats:p>","DOI":"10.1177\/0037549719881204","type":"journal-article","created":{"date-parts":[[2019,10,28]],"date-time":"2019-10-28T10:24:35Z","timestamp":1572258275000},"page":"687-702","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Multi-physics coupling simulation in virtual reactors"],"prefix":"10.1177","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0547-2798","authenticated-orcid":false,"given":"Wang","family":"Xianmeng","sequence":"first","affiliation":[{"name":"School of Computer and Communication Engineering, University of Science and Technology Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wu","family":"Mingyu","sequence":"additional","affiliation":[{"name":"Division of Reactor Engineering Technology Research, China Institute of Atomic Energy, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"He","family":"Xiao","sequence":"additional","affiliation":[{"name":"School of Computer and Communication Engineering, University of Science and Technology Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wang","family":"Zhaoshun","sequence":"additional","affiliation":[{"name":"School of Computer and Communication Engineering, University of Science and Technology Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cai","family":"Yinyu","sequence":"additional","affiliation":[{"name":"School of Computer and Communication Engineering, University of Science and Technology Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Computer and Communication Engineering, University of Science and Technology Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guo","family":"Suxuan","sequence":"additional","affiliation":[{"name":"School of Computer and Communication Engineering, University of Science and Technology Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,10,28]]},"reference":[{"key":"bibr1-0037549719881204","doi-asserted-by":"publisher","DOI":"10.1016\/j.anucene.2014.09.060"},{"key":"bibr2-0037549719881204","doi-asserted-by":"publisher","DOI":"10.13182\/NSE07-A2672"},{"key":"bibr3-0037549719881204","first-page":"25","volume-title":"Proceeding of physics of fuel cycles and advanced nuclear systems: global developments (PHYSOR-2004)","author":"Weber DP"},{"key":"bibr4-0037549719881204","doi-asserted-by":"publisher","DOI":"10.1016\/j.anucene.2013.06.031"},{"key":"bibr5-0037549719881204","unstructured":"CASL. 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