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In order to enable a convenient simulation process for a variety of scenarios, we allow the user to interact with the simulated virtual environment (VE) during run time, for example, by dynamically opening\/closing doors for room ventilation and moving\/stopping agents for re-positioning their locations. We calibrate and evaluate our approach on a real-life case study\u2014simulating COVID-19 infection transmission in two kinds of scenarios: large-scale (such as the city of M\u00fcnster, Germany) and small-scale (such as the most common indoor environments\u2014classrooms, restaurants, etc.). By using the tunable parameters of our modeling approach, we can simulate and predict the effectiveness of specific anti-COVID protective measures, such as social distancing, wearing masks, self-isolation, schools closing, etc.<\/jats:p>","DOI":"10.1177\/00375497221133849","type":"journal-article","created":{"date-parts":[[2022,11,19]],"date-time":"2022-11-19T06:38:33Z","timestamp":1668839913000},"page":"327-346","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Modeling and interactive simulation of measures against infection transmission"],"prefix":"10.1177","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1088-3228","authenticated-orcid":false,"given":"Mina","family":"Abadeer","sequence":"first","affiliation":[{"name":"University of M\u00fcnster, M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameh","family":"Magharious","sequence":"additional","affiliation":[{"name":"Dell Technologies, Bothell, WA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergei","family":"Gorlatch","sequence":"additional","affiliation":[{"name":"University of M\u00fcnster, M\u00fcnster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,11,19]]},"reference":[{"key":"bibr1-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1007\/s11538-015-0113-5"},{"key":"bibr2-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2006520117"},{"key":"bibr3-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2020.105832"},{"key":"bibr4-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1177\/0037549717721754"},{"key":"bibr5-00375497221133849","author":"Kleinmeier B","year":"2019","journal-title":"arXiv preprint arXiv:190709520"},{"key":"bibr6-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2010.0142"},{"key":"bibr7-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2020.144114"},{"key":"bibr8-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1145\/3341161.3342920"},{"key":"bibr9-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1177\/0037549719885021"},{"key":"bibr10-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1955.02960180092033"},{"key":"bibr11-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a112560"},{"key":"bibr12-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00499-5"},{"key":"bibr13-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268806005875"},{"key":"bibr14-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1007\/BF02898153"},{"key":"bibr15-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0668.2006.00443.x"},{"key":"bibr16-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1016\/j.scs.2021.102719"},{"key":"bibr17-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1016\/j.scs.2020.102390"},{"key":"bibr18-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1101\/2021.02.28.21252642."},{"key":"bibr19-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1177\/0037549720975075"},{"key":"bibr20-00375497221133849","volume-title":"Proceedings of the 2021 symposium on simulation for architecture and Urban design","author":"Altamimi T","year":"2021"},{"key":"bibr21-00375497221133849","doi-asserted-by":"publisher","DOI":"10.23919\/ANNSIM52504.2021.9552040"},{"key":"bibr22-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0245787"},{"key":"bibr23-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19393-6"},{"key":"bibr24-00375497221133849","doi-asserted-by":"publisher","DOI":"10.1109\/MCSE.2020.3019744"},{"key":"bibr25-00375497221133849","unstructured":"MITRE\u2019s infectious disease analytics team. 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