{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T15:00:27Z","timestamp":1777734027449,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["INQUIRY"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>Human immunodeficiency virus (HIV) is a global public health problem. Coinfections in HIV patients are frequent complications that increase their mortality. The aim of this study was to assess coinfections and in-hospital mortality in a group of patients infected with HIV in Colombia. A retrospective longitudinal study was carried out. Patients treated in 4 highly complex clinics in Colombia between 2015 and 2023 were included. The cases were identified from International Classification of Diseases codes related to HIV. Sociodemographic, clinical, laboratory and pharmacological variables were collected. Descriptive, bivariate, and multivariable analyses were performed. Of the 249 patients identified, 79.1% were men, and the median age was 38.0\u2009years. Approximately 81.1% had a diagnosis of acquired immune deficiency syndrome (AIDS). Coinfections caused by Mycobacterium tuberculosis (24.1%) and Treponema pallidum (20.5%) were the most frequent. A total of 20.5% of the patients had sepsis, 12.4% had septic shock, and the fatality rate was 15.7%. Antibiotics and antifungals were used in 88.8% and 53.8%, respectively, of the patients. Patients with a diagnosis of HIV before admission, those infected with M. tuberculosis, and those who presented with sepsis were more likely to die, whereas patients who received antiretroviral agent treatment before admission presented a lower risk. In this study, most HIV patients were in an advanced stage of the disease. Coinfection with M. tuberculosis was common and was associated with an increased risk of death. Previous HIV diagnosis and sepsis also increased the risk. Approximately half of the patients with a previous HIV diagnosis were receiving antiretroviral therapy and had a better prognosis.<\/jats:p>","DOI":"10.1177\/00469580241288429","type":"journal-article","created":{"date-parts":[[2024,10,5]],"date-time":"2024-10-05T16:22:59Z","timestamp":1728145379000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Coinfections and In-Hospital Mortality in a Group of Patients With HIV\/AIDS: A Longitudinal Study"],"prefix":"10.1177","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4245-0101","authenticated-orcid":false,"given":"Luis Fernando","family":"Valladales-Restrepo","sequence":"first","affiliation":[{"name":"Universidad Tecnol\u00f3gica de Pereira-Audifarma S.A, Pereira, Risaralda, Colombia"},{"name":"Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas, Pereira, Risaralda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Camila","family":"Oyuela-Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas, Pereira, Risaralda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Catalina","family":"D\u00edaz-Arteaga","sequence":"additional","affiliation":[{"name":"Universidad Tecnol\u00f3gica de Pereira-Audifarma S.A, Pereira, Risaralda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Alejandra","family":"Torres-Campo","sequence":"additional","affiliation":[{"name":"Universidad Tecnol\u00f3gica de Pereira-Audifarma S.A, Pereira, Risaralda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Allyson","family":"Rengifo-Montes","sequence":"additional","affiliation":[{"name":"Universidad Tecnol\u00f3gica de Pereira-Audifarma S.A, Pereira, Risaralda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfonso Sebasti\u00e1n","family":"Erazo-De Los R\u00edos","sequence":"additional","affiliation":[{"name":"Universidad Tecnol\u00f3gica de Pereira-Audifarma S.A, Pereira, Risaralda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Sabogal-Ortiz","sequence":"additional","affiliation":[{"name":"Grupo Operador Clinico, \u00c1rea de Salud, Cali, Valle del Cauca, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel Enrique","family":"Machado-Duque","sequence":"additional","affiliation":[{"name":"Universidad Tecnol\u00f3gica de Pereira-Audifarma S.A, Pereira, Risaralda, Colombia"},{"name":"Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas, Pereira, Risaralda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2500-7658","authenticated-orcid":false,"given":"Andr\u00e9s","family":"Gaviria-Mendoza","sequence":"additional","affiliation":[{"name":"Universidad Tecnol\u00f3gica de Pereira-Audifarma S.A, Pereira, Risaralda, Colombia"},{"name":"Fundaci\u00f3n Universitaria Aut\u00f3noma de las Am\u00e9ricas, Pereira, Risaralda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge Enrique","family":"Machado-Alba","sequence":"additional","affiliation":[{"name":"Universidad Tecnol\u00f3gica de Pereira-Audifarma S.A, Pereira, Risaralda, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,10,5]]},"reference":[{"key":"bibr1-00469580241288429","unstructured":"World Health Organization. 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