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Nurses\u2019 attitudes and self-efficacy towards caring for patients with MDRB are crucial in understanding their preventive behaviour, and a pandemic may acquire extraordinary Infection Prevention and Control (IPC) measures. To explore trends in nurses\u2019 attitudes and self-efficacy when caring for patients with MDRB. This quantitative, prospective, longitudinal study used a repeated cross-sectional design. Nurses from 5 surgical wards and 2 oncology\/haematology wards were invited to participate. The data were collected via 2 instruments: the Multidrug-Resistant Bacteria Attitude Questionnaire and the General Perceived Self-Efficacy Scale. The results were summarised with descriptive statistics, and longitudinal analyses were performed with mixed linear regression. No sample size calculations were made for this study. A total of 512 responses were received, the response rates for the time points were 60% (n\u2009=\u2009131, T1), 32% (n\u2009=\u200972, T2), 47% (n\u2009=\u2009109, T3), 48% (n\u2009=\u2009108, T4), and 41% (n\u2009=\u200992, T5). No significant longitudinal changes in nurses\u2019 attitudes and self-efficacy regarding infection prevention and control when caring for patients with MDRB were found. However, a small but significant negative change in nurses\u2019 professional and emotional approach to caring for such patients was observed towards the end of the study period. A small but significant change in the nurses\u2019 self-efficacy was observed between May 2020 and March 2021, indicating an increase in infection control self-efficacy during the first year of the COVID-19 pandemic. The stable knowledge, behavioural intentions and emotional responses contradict similar international studies. Nonetheless, moderate but stable emotional responses and high self-efficacy may indicate mental resilience in the nursing workforce, a pandemic preparedness resource that should be preserved.<\/jats:p>","DOI":"10.1177\/00469580251332060","type":"journal-article","created":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T06:25:27Z","timestamp":1749536727000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Stability in Crisis: Nurses\u2019 Attitudes and Self-Efficacy Towards Caring for Patients With Multidrug-Resistant Bacteria During the Pandemic"],"prefix":"10.1177","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5075-5132","authenticated-orcid":false,"given":"Marte Johanne","family":"Tangeraas Hansen","sequence":"first","affiliation":[{"name":"Stavanger University Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidi","family":"Syre","sequence":"additional","affiliation":[{"name":"Stavanger University Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Marie Lunde","family":"Huseb\u00f8","sequence":"additional","affiliation":[{"name":"Stavanger University Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Storm","sequence":"additional","affiliation":[{"name":"Stavanger University Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingvild","family":"Dalen","sequence":"additional","affiliation":[{"name":"Stavanger University Hospital, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,6,10]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"World Health Organization. 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