{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T21:54:25Z","timestamp":1790718865478,"version":"4.1.0"},"reference-count":56,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100007937","name":"peking university","doi-asserted-by":"publisher","award":["YN2024HL03"],"award-info":[{"award-number":["YN2024HL03"]}],"id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["INQUIRY"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:p>\n                    Metabolic-associated fatty liver disease (MAFLD) is a prevalent condition associated with significant hepatic morbidity, yet evidence-based community interventions remain limited. This mixed-methods study first assessed self-management capacity and quality of life (QOL) among MAFLD patients (n\u2009=\u2009218) in community settings, revealing suboptimal self-management (mean score 2.84\u2009\u00b1\u20090.73) and moderate QOL (3.23\u2009\u00b1\u20090.77), with education level and occupation identified as predictors. Subsequently, a randomized controlled trial (RCT) evaluated a novel community-based multidisciplinary intervention (nutritional counseling, behavioral coaching, clinical monitoring) versus standard education (n\u2009=\u2009100). At 3-month follow-up, the intervention group demonstrated clinically significant improvements versus controls: greater weight reduction (\u22129.76 vs 0.11\u2009kg;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.028), body mass index (BMI) decrease (\u22123.01 vs 0.28\u2009kg\/m\u00b2;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.006), and QOL enhancement (+8.97 vs. +2.83 points;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.002). Significant metabolic and hepatic improvements included reduced liver steatosis (controlled attenuation parameter [CAP]: \u221229\u2009dB\/m;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.001), lower liver enzymes (alanine aminotransferase [ALT]: \u221212\u2009U\/L,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.039; aspartate aminotransferase [AST]: \u22125.5\u2009U\/L,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.015), and decreased fasting glucose (\u22120.97\u2009mmol\/L;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.026). This scalable multidisciplinary model effectively enhances self-management adherence, improves metabolic health and hepatic parameters, and boosts QOL in MAFLD, offering a resource-efficient strategy for reducing chronic disease burden in primary care.\n                  <\/jats:p>","DOI":"10.1177\/00469580251380071","type":"journal-article","created":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T08:23:20Z","timestamp":1761380600000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Enhancing MAFLD Care: Efficacy of a Multidisciplinary Community Intervention on Self-Management and Hepatic Outcomes"],"prefix":"10.1177","volume":"62","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9037-9611","authenticated-orcid":false,"given":"Huan-Jing","family":"Cai","sequence":"first","affiliation":[{"name":"Peking University International Hospital, Beijing, 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