{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:01:44Z","timestamp":1777906904981,"version":"3.51.4"},"reference-count":18,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2003,7,1]],"date-time":"2003-07-01T00:00:00Z","timestamp":1057017600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2003,7]]},"abstract":"<jats:p>Dengue haemorrhagic fever (DHF) is recognized as a leading cause of hospitalization and death among children in many Southeast Asian countries. This study reviews the case fatality rates of DHF cases admitted to a referral hospital in Cebu (Philippines) over the past 5 years.<\/jats:p>\n                  <jats:p>Information on patients 14 years old or younger admitted from 1 January 1997 to 31 December 2001 with the final clinical diagnosis of DHF was collated and analysed. Case fatality rates were compared before and after a standardized management protocol was implemented by the healthcare staff and after introduction of revisions to that protocol. The case fatality rate during the 2-year periods prior and after introduction of the management protocol decreased significantly from 197\/2644 (7.45%) to 39\/1182 (3.30%) ( P&lt;0.01). Following the introduction of revisions to the protocol, the case fatality was reduced even further to 52\/1697 (3.06%) ( P=0.7).<\/jats:p>\n                  <jats:p>In this government hospital the introduction of a standardized management protocol for DHF was associated with a significant improvement in the case fatality rate of hospitalized children with clinically diagnosed DHF. However, compared with reports from hospitals in other dengue-endemic countries, the improvement has been slow. Possible ways to decrease fatality rates further have been identified.<\/jats:p>","DOI":"10.1177\/004947550303300312","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T08:46:30Z","timestamp":1484297190000},"page":"156-159","source":"Crossref","is-referenced-by-count":6,"title":["Slow Improvement of Clinically-Diagnosed Dengue Haemorrhagic Fever Case Fatality Rates"],"prefix":"10.1177","volume":"33","author":[{"given":"Nelma S","family":"Magpusao","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Southern Islands Medical Center, Cebu City, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan","family":"Monteclar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Southern Islands Medical Center, Cebu City, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacqueline L","family":"Deen","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Southern Islands Medical Center, Cebu City, Philippines"},{"name":"International Vaccine Institute, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2003,7,1]]},"reference":[{"key":"bibr1-004947550303300312","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)12483-7"},{"key":"bibr2-004947550303300312","first-page":"193","volume":"75","author":"World Health Organization","year":"2000","journal-title":"Wkly Epidemiol Record"},{"key":"bibr3-004947550303300312","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(00)90416-4"},{"key":"bibr4-004947550303300312","first-page":"131","volume":"28","author":"Shope RE","year":"1997","journal-title":"Southeast Asian J Trop Med Pub Health"},{"key":"bibr5-004947550303300312","volume-title":"Dengue Haemorrhagic Fever: Diagnosis, Treatment and Control","author":"World Health Organization","year":"1986"},{"key":"bibr6-004947550303300312","volume-title":"Dengue Haemorrhagic Fever: Diagnosis, Treatment, Prevention and Control","author":"World Health Organization","year":"1997","edition":"2"},{"key":"bibr7-004947550303300312","volume-title":"Guidelines for Treatment of Dengue Fever\/Dengue Hemorrhagic Fever in Small Hospitals","author":"World Health Organization","year":"1999"},{"key":"bibr8-004947550303300312","volume-title":"Report on the Epidemiological Profile of Dengue Fever\/Dengue Haemorrhagic Fever in Mekong Region Countries 1990\u20131999","author":"Guha-Sapir D","year":"2000"},{"key":"bibr9-004947550303300312","volume-title":"Surveillance Data: National Epidemic Sentinel Surveillance System Report","author":"Department of Health","year":"2000"},{"key":"bibr10-004947550303300312","volume-title":"The WHO Report on Global Surveillance of Epidemic-prone Infectious Diseases","author":"World Health 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