{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:02:15Z","timestamp":1777906935791,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2004,4]]},"abstract":"<jats:p>Aural swabs were collected from 250 patients with chronic suppurative otitis media (CSOM) (tubotympanic disease). Duration of ear discharge was more than 6 months for culture and sensitivity test. The disease was unilateral in 178(71.2%)and bilateral in 72 (28.8%) patients. From a total of 322 aural swab cultures, 324 organisms were isolated with predominance of Pseudomonas aerugimosa (36.4%) followed by Staphylococcus aureus (30.2%). All the isolated Gram-negative organisms showed in vitro sensitivity to ciprofloxacin, amikacin, ofloxacin, and gentamycin whereas cloxacillin, ofloxacin, erythromycin, ciprofloxacin, gentamicin and tetracycline were more effective against Gram-positive isolates. Most isolates were resistant to amoxycillin. It is concluded that ciprofloxacin is preferred to aminoglycosides as an important tool in the treatment of CSOM because of its lower cost, lack of ototoxicity and availability astopical oral preparations.<\/jats:p>","DOI":"10.1177\/004947550403400218","type":"journal-article","created":{"date-parts":[[2017,1,15]],"date-time":"2017-01-15T18:19:14Z","timestamp":1484504354000},"page":"102-104","source":"Crossref","is-referenced-by-count":16,"title":["Bacteriological Profile in Chronic Suppurative Otitis Media in Eastern Nepal"],"prefix":"10.1177","volume":"34","author":[{"given":"Satyender","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harmeet Singh","family":"Rehan","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Lady Hardinge Medical College, New Delhi, 1100001"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun","family":"Goyal","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, University College of Medical Sciences and GTB Hospital, New Delhi, 95 India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashok Kumar","family":"Jha","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanjib","family":"Upadhyaya","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S C","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2004,4,1]]},"reference":[{"key":"bibr1-004947550403400218","first-page":"215","volume":"3","author":"Shenoi PM","year":"1987","journal-title":"Scott Brown's Otolaryngology, 5th edn. 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